Literature DB >> 7764084

Bone morphogenetic proteins (BMPs): therapeutic potential in healing bony defects.

E A Wang1.   

Abstract

The bone morphogenetic proteins (BMPs) belong to a family of proteins that also includes the transforming growth factors beta (TGF-beta) and the inhibins. The BMPs can induce new bone formation in ectopic sites and therefore have enormous potential in bone repair. Studies of fracture-repair models involving BMP-2 suggest that this factor will be useful in healing bony defects in humans. Basic research on the BMPs predict a variety of activities on morphogenesis in systems other than cartilage and bone.

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Year:  1993        PMID: 7764084     DOI: 10.1016/0167-7799(93)90096-R

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  14 in total

1.  Effect of recombinant human bone morphogenetic protein-2 on the osseointegration of dental implants: a biomechanics study.

Authors:  Nikitas Sykaras; Anthony M Iacopino; Robert G Triplett; Victoria A Marker
Journal:  Clin Oral Investig       Date:  2004-07-29       Impact factor: 3.573

2.  [Injectable carrier system for growth factor application in minimally invasive stimulation of bone healing].

Authors:  H Windhagen; F Witte; F Thorey; C Hurschler; C J Wirth
Journal:  Orthopade       Date:  2004-12       Impact factor: 1.087

3.  Advances in Polymer and Polymeric Nanostructures for Protein Conjugation.

Authors:  Daniella C González-Toro; S Thayumanavan
Journal:  Eur Polym J       Date:  2013-10-01       Impact factor: 4.598

4.  Erythropoietin modulates the structure of bone morphogenetic protein 2-engineered cranial bone.

Authors:  Hongli Sun; Younghun Jung; Yusuke Shiozawa; Russell S Taichman; Paul H Krebsbach
Journal:  Tissue Eng Part A       Date:  2012-08-10       Impact factor: 3.845

5.  Enhancement of bone growth by sustained delivery of recombinant human bone morphogenetic protein-2 in a polymeric matrix.

Authors:  B H Woo; B F Fink; R Page; J A Schrier; Y W Jo; G Jiang; M DeLuca; H C Vasconez; P P DeLuca
Journal:  Pharm Res       Date:  2001-12       Impact factor: 4.200

6.  The enhancement of osteogenesis by nano-fibrous scaffolds incorporating rhBMP-7 nanospheres.

Authors:  Guobao Wei; Qiming Jin; William V Giannobile; Peter X Ma
Journal:  Biomaterials       Date:  2007-01-08       Impact factor: 12.479

7.  Nucleoporin 62-like protein activates canonical Wnt signaling through facilitating the nuclear import of β-catenin in zebrafish.

Authors:  Xiaojie Yang; Qilin Gu; Li Lin; Shaoyang Li; Shan Zhong; Qing Li; Zongbin Cui
Journal:  Mol Cell Biol       Date:  2015-01-20       Impact factor: 4.272

8.  Mesenchymal stem cells with rhBMP-2 inhibits the growth of canine osteosarcoma cells.

Authors:  Rose Eli Grassi Rici; Dayane Alcântara; Paula Fratini; Cristiane Valverde Wenceslau; Carlos Eduardo Ambrósio; Maria Angelica Miglino; Durvanei Augusto Maria
Journal:  BMC Vet Res       Date:  2012-02-22       Impact factor: 2.741

9.  Evaluation of a thiolated chitosan scaffold for local delivery of BMP-2 for osteogenic differentiation and ectopic bone formation.

Authors:  In-Ho Bae; Byung-Chul Jeong; Min-Suk Kook; Sun-Hun Kim; Jeong-Tae Koh
Journal:  Biomed Res Int       Date:  2013-08-20       Impact factor: 3.411

Review 10.  Vitamin D and gene networks in human osteoblasts.

Authors:  Jeroen van de Peppel; Johannes P T M van Leeuwen
Journal:  Front Physiol       Date:  2014-04-09       Impact factor: 4.566

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