Literature DB >> 7764041

Alphaviruses--vectors for the expression of heterologous genes.

S Schlesinger1.   

Abstract

DNA viruses and retroviruses are well established as vectors for the expression of heterologous genes, but there is increasing interest in the possibilities of using RNA viruses, which do not replicate through a DNA intermediate, for this purpose. This article summarizes some of the general properties of RNA viruses and concentrates on one class of RNA viruses--the alphaviruses--and their potential as expression vectors.

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Year:  1993        PMID: 7764041      PMCID: PMC7172487          DOI: 10.1016/0167-7799(93)90070-P

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  17 in total

1.  Recombination between Sindbis virus RNAs.

Authors:  B G Weiss; S Schlesinger
Journal:  J Virol       Date:  1991-08       Impact factor: 5.103

2.  Rescue of synthetic analogs of respiratory syncytial virus genomic RNA and effect of truncations and mutations on the expression of a foreign reporter gene.

Authors:  P L Collins; M A Mink; D S Stec
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-01       Impact factor: 11.205

3.  Infection initiated by the RNA pregenome of a DNA virus.

Authors:  M J Huang; J Summers
Journal:  J Virol       Date:  1991-10       Impact factor: 5.103

4.  Amplification, expression, and packaging of foreign gene by influenza virus.

Authors:  W Luytjes; M Krystal; M Enami; J D Parvin; P Palese
Journal:  Cell       Date:  1989-12-22       Impact factor: 41.582

5.  Promoter for Sindbis virus RNA-dependent subgenomic RNA transcription.

Authors:  R Levis; S Schlesinger; H V Huang
Journal:  J Virol       Date:  1990-04       Impact factor: 5.103

6.  RNA viruses as gene expression vectors.

Authors:  H V Huang; C M Rice; C Xiong; S Schlesinger
Journal:  Virus Genes       Date:  1989-09       Impact factor: 2.332

7.  Complementation between Sindbis viral RNAs produces infectious particles with a bipartite genome.

Authors:  U Geigenmüller-Gnirke; B Weiss; R Wright; S Schlesinger
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-15       Impact factor: 11.205

8.  Evidence for specificity in the encapsidation of Sindbis virus RNAs.

Authors:  B Weiss; H Nitschko; I Ghattas; R Wright; S Schlesinger
Journal:  J Virol       Date:  1989-12       Impact factor: 5.103

9.  A new generation of animal cell expression vectors based on the Semliki Forest virus replicon.

Authors:  P Liljeström; H Garoff
Journal:  Biotechnology (N Y)       Date:  1991-12

10.  Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.

Authors:  C S Hahn; Y S Hahn; T J Braciale; C M Rice
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205

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  29 in total

Review 1.  Nucleic acid vaccines: tasks and tactics.

Authors:  B S McKenzie; A J Corbett; J L Brady; C M Dyer; R A Strugnell; S J Kent; D R Kramer; J S Boyle; A M Lew
Journal:  Immunol Res       Date:  2001       Impact factor: 2.829

2.  Alphavirus replicase protein NSP1 induces filopodia and rearrangement of actin filaments.

Authors:  P Laakkonen; P Auvinen; P Kujala; L Kääriäinen
Journal:  J Virol       Date:  1998-12       Impact factor: 5.103

3.  Construction of a genome-length cDNA clone for human astrovirus serotype 1 and synthesis of infectious RNA transcripts.

Authors:  U Geigenmüller; N H Ginzton; S M Matsui
Journal:  J Virol       Date:  1997-02       Impact factor: 5.103

4.  Optogenetic manipulation of medullary neurons in the locust optic lobe.

Authors:  Hongxia Wang; Richard B Dewell; Markus U Ehrengruber; Eran Segev; Jacob Reimer; Michael L Roukes; Fabrizio Gabbiani
Journal:  J Neurophysiol       Date:  2018-08-15       Impact factor: 2.714

5.  Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection.

Authors:  Roberto Malinow; Yasunori Hayashi; Mirjana Maletic-Savatic; Shahid H Zaman; Jean-Christophe Poncer; Song-Hai Shi; José A Esteban; Pavel Osten; Ken Seidenman
Journal:  Cold Spring Harb Protoc       Date:  2010-04

6.  Efficient expression by an alphavirus replicon of a functional ribozyme targeted to human immunodeficiency virus type 1.

Authors:  S M Smith; F Maldarelli; K T Jeang
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

7.  Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells.

Authors:  I Frolov; S Schlesinger
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

8.  Bc1-2 protects mice against fatal alphavirus encephalitis.

Authors:  B Levine; J E Goldman; H H Jiang; D E Griffin; J M Hardwick
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-14       Impact factor: 11.205

9.  Regulated expression of a Sindbis virus replicon by herpesvirus promoters.

Authors:  L Ivanova; S Schlesinger; P D Olivo
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103

10.  Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons.

Authors:  D S Park; B Levine; G Ferrari; L A Greene
Journal:  J Neurosci       Date:  1997-12-01       Impact factor: 6.167

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