Literature DB >> 7763546

Steroid hydroxylation with free and immobilized cells of Penicillium raistrickii in the presence of beta-cyclodextrin.

D Schlosser1, S Irrgang, H P Schmauder.   

Abstract

Free and Ca-alginate-immobilized cells of Penicillium raistrickii i 477 were used for 15 alpha-hydroxylation of 13-ethyl-gon-4-en-3,17-dione. The product formation of both free and immobilized cells was increased in the presence of beta-cyclodextrin, in comparison with reactions carried out in the presence of methanol. Application of beta-cyclodextrin led to increasing solubility of the steroid substrate. The fungus was able to utilize beta-cyclodextrin as a carbon source.

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Year:  1993        PMID： 7763546     DOI： 10.1007/BF00166841

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN： 0175-7598            Impact factor:   4.813


  3 in total

Review 1.  Application of immobilized cells for biotransformations of steroids.

Authors:  H P Schmauder; D Schlosser; T Günther; A Hattenbach; J Sauerstein; F Jungnickel; H Augsten
Journal:  J Basic Microbiol       Date:  1991       Impact factor: 2.281

2.  11beta-Hydroxylation of Cortexolone (Reichstein Compound S) to Hydrocortisone by Curvularia lunata Entrapped in Photo-Cross-Linked Resin Gels.

Authors:  K Sonomoto; M M Hoq; A Tanaka; S Fukui
Journal:  Appl Environ Microbiol       Date:  1983-02       Impact factor: 4.792

3.  15 alpha-hydroxylation of 13-ethyl-gon-4-ene-3,17-dione using a hyphal fungus immobilized in calcium alginate gel beads.

Authors:  D Schlosser; H P Schmauder
Journal:  J Basic Microbiol       Date:  1991       Impact factor: 2.281
  3 in total
  1 in total

1.  Influence of hydroxypropyl-β-cyclodextrin on phytosterol biotransformation by different strains of Mycobacterium neoaurum.

Authors:  Yan-Bing Shen; Min Wang; Hua-Nan Li; Yi-Bo Wang; Jian-Mei Luo
Journal:  J Ind Microbiol Biotechnol       Date:  2012-05-22       Impact factor: 3.346
  1 in total

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