Literature DB >> 7763378

Transcription factor based therapeutics: drugs of the future?

M G Peterson1, V R Baichwal.   

Abstract

During the past decade there has been an explosion of information relating to our understanding of eukaryotic gene expression. The identification of transcription factors as the key regulatory molecules in this process, and the analysis of their structure and function have revealed that these proteins are potential targets for therapeutic intervention.

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Year:  1993        PMID： 7763378     DOI： 10.1016/0167-7799(93)90069-L

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN： 0167-7799            Impact factor:   19.536


  5 in total

Review 1.  Transcription factor-based drug design in anticancer drug development.

Authors:  A G Papavassiliou
Journal:  Mol Med       Date:  1997-12       Impact factor: 6.354

2.  Use of a yeast expression system for the isolation and analysis of drug-resistant mutants of a mammalian phosphodiesterase.

Authors:  R Pillai; K Kytle; A Reyes; J Colicelli
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205

3.  Antifungal azoxybacilin exhibits activity by inhibiting gene expression of sulfite reductase.

Authors:  Y Aoki; M Yamamoto; S M Hosseini-Mazinani; N Koshikawa; K Sugimoto; M Arisawa
Journal:  Antimicrob Agents Chemother       Date:  1996-01       Impact factor: 5.191

Review 4.  Novel synthetic biology approaches for developmental systems.

Authors:  Christine Ho; Leonardo Morsut
Journal:  Stem Cell Reports       Date:  2021-05-11       Impact factor: 7.765

5.  Targeting gene transcription: a new strategy to down-regulate c-erbB-2 expression in mammary carcinoma.

Authors:  D P Hollywood; H C Hurst
Journal:  Br J Cancer       Date:  1995-04       Impact factor: 7.640
  5 in total

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