Literature DB >> 7763247

Inhibition of glycogen synthase kinase-3 by insulin in cultured human skeletal muscle myoblasts.

A C Borthwick1, A M Wells, J J Rochford, S J Hurel, D M Turnbull, S J Yeaman.   

Abstract

The acute effects of insulin on the activity of glycogen synthase kinase 3 (GSK-3) have been investigated both in the rat L6 muscle cell line and in cultured human myoblasts. The alpha and beta isoforms of GSK-3 are present in both cell types, with the beta isoform being predominant in the human cells. Insulin causes a rapid inactivation of both isoforms in both cell lines, with 50% inactivation being observed in the human myoblasts.

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Year:  1995        PMID： 7763247     DOI： 10.1006/bbrc.1995.1721

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  8 in total

Review 1.  Molecular mechanisms for the control of translation by insulin.

Authors:  C G Proud; R M Denton
Journal:  Biochem J       Date:  1997-12-01       Impact factor: 3.857

2.  Effects of diabetes, vanadium, and insulin on glycogen synthase activation in Wistar rats.

Authors:  Sabina Semiz; Chris Orvig; John H McNeill
Journal:  Mol Cell Biochem       Date:  2002-02       Impact factor: 3.396

3.  Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

Authors:  S J Hurel; J J Rochford; A C Borthwick; A M Wells; J R Vandenheede; D M Turnbull; S J Yeaman
Journal:  Biochem J       Date:  1996-12-15       Impact factor: 3.857

4.  AICAR positively regulate glycogen synthase activity and LDL receptor expression through Raf-1/MEK/p42/44MAPK/p90RSK/GSK-3 signaling cascade.

Authors:  Hsiang-Ming Wang; Sonya Mehta; Rishipal Bansode; Wei Huang; Kamal D Mehta
Journal:  Biochem Pharmacol       Date:  2007-09-01       Impact factor: 5.858

5.  GSK-3beta and control of glucose metabolism and insulin action in human skeletal muscle.

Authors:  T P Ciaraldi; L Carter; S Mudaliar; R R Henry
Journal:  Mol Cell Endocrinol       Date:  2009-06-06       Impact factor: 4.102

6.  Oral treatment with vanadium of Zucker fatty rats activates muscle glycogen synthesis and insulin-stimulated protein phosphatase-1 activity.

Authors:  Sabina Semiz; John H McNeill
Journal:  Mol Cell Biochem       Date:  2002-07       Impact factor: 3.396

7.  High density lipoprotein (HDL) promotes glucose uptake in adipocytes and glycogen synthesis in muscle cells.

Authors:  Qichun Zhang; Yun Zhang; Haihua Feng; Rui Guo; Lai Jin; Rong Wan; Lina Wang; Cheng Chen; Shengnan Li
Journal:  PLoS One       Date:  2011-08-19       Impact factor: 3.240

8.  Antidiabetic Properties of Azardiracta indica and Bougainvillea spectabilis: In Vivo Studies in Murine Diabetes Model.

Authors:  Menakshi Bhat; Sandeepkumar K Kothiwale; Amruta R Tirmale; Shobha Y Bhargava; Bimba N Joshi
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-18       Impact factor: 2.629
  8 in total

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