Literature DB >> 77629

Clinical, hormonal and ultrastructure studies of a virilizing hepatoblastoma.

E V Kumar, L Kumar, I C Pathak, R J Dash, V V Joshi.   

Abstract

Virilizing hepatoblastoma was found to be the cause of precocious puberty in a 3 1/4-year-old boy. Both human chorionic gonadotropins and alphafetoprotein in increased amounts were detected in serum and tumor tissue. These substances disappeared from the blood after removal of the tumor. Ultrastructure studies revealed the presence of dense, membrane bound, secretory granules responsible for the hormone production.

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Year:  1978        PMID: 77629     DOI: 10.1111/j.1651-2227.1978.tb16340.x

Source DB:  PubMed          Journal:  Acta Paediatr Scand        ISSN: 0001-656X


  4 in total

1.  Virilizing hepatoblastoma--significance of alpha-1-fetoprotein and human chorionic gonadotropin as tumor markers in diagnosis and follow-up.

Authors:  U E Heinrich; M Bolkenius; R Daum; H C Oppermann; O Mehls; W E Brandeis
Journal:  Eur J Pediatr       Date:  1981-02       Impact factor: 3.183

2.  Immunocytochemical identification of human chorionic gonadotropin- and alpha-fetoprotein-producing cells of hepatoblastoma associated with precocious puberty.

Authors:  A Nakagawara; K Ikeda; Y Hayashida; M Tsuneyoshi; M Enjoji; A Kawaoi
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1982

3.  Production of human chorionic gonadotrophin by a hepatoblastoma resulting in precocious puberty.

Authors:  R Beach; P Betts; M Radford; H Millward-Sadler
Journal:  J Clin Pathol       Date:  1984-07       Impact factor: 3.411

4.  Precocious puberty in an infant with hepatoblastoma: a case report.

Authors:  Usama Al-Jumaily; Ibrahim Sammour; Fadi Al-Muhaisen; Fatenah Ajlouni; Iyad Sultan
Journal:  J Med Case Rep       Date:  2011-08-30
  4 in total

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