| Literature DB >> 7762275 |
C H Romero1, T Barrett, R P Kitching, C Bostock, D N Black.
Abstract
Goats were protected against a lethal challenge of peste des petits ruminants (PPR) virus following vaccination with a recombinant capripoxvirus containing either the fusion (F) gene of rinderpest virus or the haemagglutinin (H) gene of rinderpest virus. The H gene recombinant produced high titres of neutralizing antibody to rinderpest virus in the vaccinated goats, whereas the F gene recombinant failed to stimulate detectable levels of neutralizing antibody. A similar response to the two recombinant vaccines has previously been reported for cattle. Neither recombinant produced detectable levels of specific antibodies to PPR virus.Entities:
Mesh:
Substances:
Year: 1995 PMID: 7762275 DOI: 10.1016/0264-410x(95)80008-2
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641