Literature DB >> 7757417

A convenient synthesis of nucleoside monophosphate-N-acetylneuraminic acids (NMP-Neu5Ac).

T J Martin1, H Braun, R R Schmidt.   

Abstract

Reaction of sialyl phosphites 2a,b with acetyl-protected ribonucleoside monophosphates 3C, 3U, 3A and 3G furnished without addition of a catalyst directly the corresponding beta-configurated sialyl ribonucleoside monophosphates 4C, 4U, 4A and 4G, respectively. Treatment of these compounds with sodium methanolate in methanol and sodium hydroxide afforded the disodium salts of CMP-Neu5Ac (1C), UMP-Neu5Ac (1U), AMP-Neu5Ac (1A), and GMP-Neu5Ac (1G).

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Year:  1994        PMID: 7757417     DOI: 10.1016/s0968-0896(00)82071-4

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

1.  Ceramide-1-phosphate sugars: new types of glycophospholipids.

Authors:  T J Martin; G Dufner; B Kratzer; R R Schmidt
Journal:  Glycoconj J       Date:  1996-08       Impact factor: 2.916

2.  Docking-guided rational engineering of a macrolide glycosyltransferase glycodiversifies epothilone B.

Authors:  Peng Zhang; Lijuan Zhang; Xukai Jiang; Xiao-Tong Diao; Shuang Li; Dan-Dan Li; Zheng Zhang; Junqiang Fang; Ya-Jie Tang; Da-Lei Wu; Changsheng Wu; Yue-Zhong Li
Journal:  Commun Biol       Date:  2022-01-27
  2 in total

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