Literature DB >> 7757415

Five-membered ring azasugars as potent inhibitors of alpha-L-rhamnosidase (naringinase) from Penicillium decumbens.

L Provencher1, D H Steensma, C H Wong.   

Abstract

Five-membered ring azasugars with the L-rhamnose configuration were synthesized as inhibitors of alpha-L-rhamnosidase from Penicillium decumbens. All compounds tested were in the microM or sub-microM range. Substitution at the nitrogen shifted the inhibition mechanism from mixed to competitive.

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Year:  1994        PMID: 7757415     DOI: 10.1016/s0968-0896(00)82069-6

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  4 in total

1.  Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S.

Authors:  Sri Kumar Veleti; Cecile Petit; Donald R Ronning; Steven J Sucheck
Journal:  Org Biomol Chem       Date:  2017-05-10       Impact factor: 3.876

2.  Alternative synthesis and antibacterial evaluation of 1,5-dideoxy-1,5-imino-L-rhamnitol.

Authors:  Suresh Dharuman; Yichen Wang; David Crich
Journal:  Carbohydr Res       Date:  2015-11-04       Impact factor: 2.104

3.  Synthesis of a poly-hydroxypyrolidine-based inhibitor of Mycobacterium tuberculosis GlgE.

Authors:  Sri Kumar Veleti; Jared J Lindenberger; Sandeep Thanna; Donald R Ronning; Steven J Sucheck
Journal:  J Org Chem       Date:  2014-08-26       Impact factor: 4.354

4.  Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors.

Authors:  Jared J Lindenberger; Sri Kumar Veleti; Brittney N Wilson; Steven J Sucheck; Donald R Ronning
Journal:  Sci Rep       Date:  2015-08-06       Impact factor: 4.379

  4 in total

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