Literature DB >> 77574

Effect of lindane on pregnancy in the rabbit and rat.

A K Palmer, A M Bottomley, A N Worden, H Frohberg, A Bauer.   

Abstract

There was no evidence of any teratogenic effect of lindane when administered during pregnancy at levels equivalent to 5, and 15 mg/kg body weight to New Zealand White rabbits from days 6 to 18 inclusive, or to CFY rats from days 6 to 16 inclusive. These findings are consistent with the negative teratogenicity results in mice mutagenicity studies and 3-generation rat reproduction studies already reported.

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Year:  1978        PMID: 77574     DOI: 10.1016/0300-483x(78)90006-9

Source DB:  PubMed          Journal:  Toxicology        ISSN: 0300-483X            Impact factor:   4.221


  5 in total

Review 1.  Pharmacotherapy of ectoparasitic infections.

Authors:  T C Roos; M Alam; S Roos; H F Merk; D R Bickers
Journal:  Drugs       Date:  2001       Impact factor: 9.546

2.  Mutagenicity-carcinogenicity as related to teratogenic activity.

Authors:  M Alia; E Laborda; F A Antón
Journal:  Bull Environ Contam Toxicol       Date:  1992-02       Impact factor: 2.151

3.  Effect of lead on fetal development in rats fed with 8% casein diet.

Authors:  D K Saxena; B Lal; S V Chandra
Journal:  Bull Environ Contam Toxicol       Date:  1987-10       Impact factor: 2.151

Review 4.  Safety of Topical Medications for Scabies and Lice in Pregnancy.

Authors:  Viral M Patel; W Clark Lambert; Robert A Schwartz
Journal:  Indian J Dermatol       Date:  2016 Nov-Dec       Impact factor: 1.494

5.  Sustained inhibition of rat myometrial gap junctions and contractions by lindane.

Authors:  Rita K Loch-Caruso; Kay A Criswell; Carmen M Grindatti; Kelly A Brant
Journal:  Reprod Biol Endocrinol       Date:  2003-10-03       Impact factor: 5.211

  5 in total

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