Literature DB >> 7757019

Profiles for the analysis of immunoglobulin sequences: comparison of V gene subgroups.

L Harris1, J Bajorath.   

Abstract

A format for the structure-oriented analysis of immunoglobulin (Ig) variable region sequences is presented and applied to generate sequence profiles for comparison of heavy- and light-chain subgroups. The profile allows simultaneous evaluation of sequences and structural information and can be used for a number of different applications.

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Year:  1995        PMID： 7757019      PMCID： PMC2143066          DOI： 10.1002/pro.5560040217

Source DB:  PubMed          Journal:  Protein Sci        ISSN： 0961-8368            Impact factor:   6.725


  3 in total

1.  Structural invariants of antigen binding: comparison of immunoglobulin VL-VH and VL-VL domain dimers.

Authors:  J Novotný; E Haber
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205

2.  Human-engineered monoclonal antibodies retain full specific binding activity by preserving non-CDR complementarity-modulating residues.

Authors:  G M Studnicka; S Soares; M Better; R E Williams; R Nadell; A H Horwitz
Journal:  Protein Eng       Date:  1994-06

3.  Three-dimensional model of the BR96 monoclonal antibody variable fragment.

Authors:  J Bajorath
Journal:  Bioconjug Chem       Date:  1994 May-Jun       Impact factor: 4.774
  3 in total
  1 in total

1.  The VH framework region 1 as a target of efficient mutagenesis for generating a variety of affinity-matured scFv mutants.

Authors:  Yuki Kiguchi; Hiroyuki Oyama; Izumi Morita; Yasuhiro Nagata; Naoko Umezawa; Norihiro Kobayashi
Journal:  Sci Rep       Date:  2021-04-15       Impact factor: 4.379
  1 in total

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