Literature DB >> 7755919

Traditional vaginal agents: use and association with HIV infection in Malawian women.

G A Dallabetta1, P G Miotti, J D Chiphangwi, G Liomba, J K Canner, A J Saah.   

Abstract

OBJECTIVES: To assess the prevalence of traditional vaginal agent use in Malawian women and its association with HIV infection.
METHODS: Consenting, consecutive antenatal women were administered a questionnaire and screened for sexually transmitted diseases (STD) including HIV.
RESULTS: Of the 6603 consenting women, 886 (13%) reported using intravaginal agents for tightening and 2222 (34%) for self-treatment of vaginal discharge and itching. A higher proportion of HIV-infected than uninfected women (17% versus 14%) reported use of intravaginal agents for treatment (odds ratio, 1.29; 95% confidence interval, 1.05-1.57), but no difference in HIV status was found when these agents were used for tightening. In multivariate analysis, vaginal agent use for treatment was independently associated with HIV seropositivity.
CONCLUSIONS: The association of HIV infection with vaginal agents for self-treatment, but not for tightening, suggests that STD may play a role or that vaginal agents are used differently for the two purposes. In addition to a small increased risk of HIV infection associated with vaginal agent use, these agents may interfere with condom effectiveness or acceptability of vaginal microbicides.

Entities:  

Keywords:  Africa; Africa South Of The Sahara; Behavior; Biology; Coitus; Correlation Studies; Delivery Of Health Care; Demographic Factors; Developing Countries; Diseases; Eastern Africa; English Speaking Africa; Health; Health Services; Hiv Infections; Infections; Malawi; Medicine; Medicine, Traditional; Population; Population Characteristics; Pregnant Women; Reproduction; Reproductive Tract Infections; Risk Factors; Sex Behavior; Sexually Transmitted Diseases; Statistical Studies; Studies; Vaginal Abnormalities; Vaginal Injury; Viral Diseases

Mesh:

Substances:

Year:  1995        PMID: 7755919

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


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