Literature DB >> 7755607

A macrocircular ellagitannin, oenothein B, suppresses mouse mammary tumor gene expression via inhibition of poly(ADP-ribose) glycohydrolase.

K Aoki1, H Maruta, F Uchiumi, T Hatano, T Yoshida, S Tanuma.   

Abstract

Oenothein B, a macrocircular dimeric ellagitannin, was found to be a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B suppressed glucocorticoid-sensitive mouse mammary tumor virus (MMTV) transcription in 34I cells. This suppression was accompanied by inhibition of glucocorticoid-induced endogeneous de-poly(ADP-ribosyl)ation of high mobility group (HMG) 14 and 17 proteins. These results suggest that de-poly(ADP-ribosyl)ation of these proteins may be closely connected with the events initiating glucocorticoid-sensitive MMTV gene transcription.

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Year:  1995        PMID： 7755607     DOI： 10.1006/bbrc.1995.1665

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

Review 1.  Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions.

Authors:  D D'Amours; S Desnoyers; I D'Silva; G G Poirier
Journal:  Biochem J       Date:  1999-09-01       Impact factor: 3.857

2.  Immunomodulatory activity of oenothein B isolated from Epilobium angustifolium.

Authors:  Igor A Schepetkin; Liliya N Kirpotina; Larissa Jakiw; Andrei I Khlebnikov; Christie L Blaskovich; Mark A Jutila; Mark T Quinn
Journal:  J Immunol       Date:  2009-10-21       Impact factor: 5.422

3.  Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice.

Authors:  Ulrich Cortes; Wei-Min Tong; Donna L Coyle; Mirella L Meyer-Ficca; Ralph G Meyer; Virginie Petrilli; Zdenko Herceg; Elaine L Jacobson; Myron K Jacobson; Zhao-Qi Wang
Journal:  Mol Cell Biol       Date:  2004-08       Impact factor: 4.272

Review 4.  Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed).

Authors:  Igor A Schepetkin; Andrew G Ramstead; Liliya N Kirpotina; Jovanka M Voyich; Mark A Jutila; Mark T Quinn
Journal:  Phytother Res       Date:  2016-05-24       Impact factor: 5.878

5.  Effects of Tannic Acid, Green Tea and Red Wine on hERG Channels Expressed in HEK293 Cells.

Authors:  Xi Chu; Yusong Guo; Bingyuan Xu; Wenya Li; Yue Lin; Xiaorun Sun; Chunhua Ding; Xuan Zhang
Journal:  PLoS One       Date:  2015-12-01       Impact factor: 3.240

6.  Transcriptional profile of Paracoccidioides induced by oenothein B, a potential antifungal agent from the Brazilian Cerrado plant Eugenia uniflora.

Authors:  Patrícia Fernanda Zambuzzi-Carvalho; Patrícia Kott Tomazett; Suzana Costa Santos; Pedro Henrique Ferri; Clayton Luiz Borges; Wellington Santos Martins; Célia Maria de Almeida Soares; Maristela Pereira
Journal:  BMC Microbiol       Date:  2013-10-12       Impact factor: 3.605

Review 7.  Chemical and Biological Significance of Oenothein B and Related Ellagitannin Oligomers with Macrocyclic Structure.

Authors:  Takashi Yoshida; Morio Yoshimura; Yoshiaki Amakura
Journal:  Molecules       Date:  2018-03-02       Impact factor: 4.411
  7 in total

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