OBJECTIVE: Two experiments were designed to test the hypothesis that the amount of alcohol-induced impairment that a drinker expects will predict his response to alcohol and to placebo. METHOD: Social drinkers (N = 81) werefamiliarized with a laboratory motor skill task before they rated the amount of impairment on the task that they expected from a moderate dose of alcohol. The degree of change in the subjects' performance was measured during an alcohol session and a subsequent session where alcohol was expected but a placebo was received. RESULTS: Subjects who expected greater impairment displayed poorer performance under alcohol (0.35 g/kg) and under placebo. CONCLUSIONS: This evidence calls attention to the importance of expectancies as a factor that may contribute to the understanding of individual differences in behavior under alcohol and a placebo.
RCT Entities:
OBJECTIVE: Two experiments were designed to test the hypothesis that the amount of alcohol-induced impairment that a drinker expects will predict his response to alcohol and to placebo. METHOD: Social drinkers (N = 81) were familiarized with a laboratory motor skill task before they rated the amount of impairment on the task that they expected from a moderate dose of alcohol. The degree of change in the subjects' performance was measured during an alcohol session and a subsequent session where alcohol was expected but a placebo was received. RESULTS: Subjects who expected greater impairment displayed poorer performance under alcohol (0.35 g/kg) and under placebo. CONCLUSIONS: This evidence calls attention to the importance of expectancies as a factor that may contribute to the understanding of individual differences in behavior under alcohol and a placebo.
Authors: Oscar H Hernández; Muriel Vogel-Sprott; Teresita C Huchín-Ramirez; Fernando Aké-Estrada Journal: Psychopharmacology (Berl) Date: 2005-12-07 Impact factor: 4.530
Authors: Remco W M Zoethout; Wilson L Delgado; Annelies E Ippel; Albert Dahan; Joop M A van Gerven Journal: Br J Clin Pharmacol Date: 2011-03 Impact factor: 4.335
Authors: Maria Testa; Mark T Fillmore; Jeanette Norris; Antonia Abbey; John J Curtin; Kenneth E Leonard; Kristin A Mariano; Margaret C Thomas; Kim J Nomensen; William H George; Carol Vanzile-Tamsen; Jennifer A Livingston; Christopher Saenz; Philip O Buck; Tina Zawacki; Michele R Parkhill; Angela J Jacques; Lenwood W Hayman Journal: Alcohol Clin Exp Res Date: 2006-02 Impact factor: 3.455