Literature DB >> 7750998

Polarized secretion of interleukin-8 by human mesothelial cells: a role in neutrophil migration.

A M Zeillemaker1, F P Mul, A A Hoynck van Papendrecht, T W Kuijpers, D Roos, P Leguit, H A Verbrugh.   

Abstract

We investigated the role of human mesothelium in an in vitro model of peritonitis with emphasis on the secretion of the neutrophil chemoattractant interleukin-8 (IL-8) and the migration of polymorphonuclear leucocytes (PMN) across monolayers of peritoneal mesothelial cells. PMN showed minimal migration across non-activated mesothelial monolayers (< 2%). However, migration was induced after mesothelial cell activation by IL-1 beta (24%) and this induced migration was significantly blocked by antibodies against IL-8 (63% inhibition; P < or = 0.01). IL-1 beta-activated mesothelial monolayers were shown to secrete IL-8 in a polarized way, which was preferentially oriented towards the apical side of the monolayer. Our results indicate that the influx of PMN into the peritoneal cavity is, at least in part, controlled by the mesothelial cell layer of the peritoneal membrane.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7750998      PMCID： PMC1415093     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  23 in total

1.  Transepithelial transport in cell culture.

Authors:  D S Misfeldt; S T Hamamoto; D R Pitelka
Journal:  Proc Natl Acad Sci U S A       Date:  1976-04       Impact factor: 11.205

Review 2.  New concepts in molecular biology and ultrastructural pathology of the peritoneum: their significance for peritoneal dialysis.

Authors:  J W Dobbie
Journal:  Am J Kidney Dis       Date:  1990-02       Impact factor: 8.860

3.  Comparison of production of transforming growth factor-beta and platelet-derived growth factor by normal human mesothelial cells and mesothelioma cell lines.

Authors:  B I Gerwin; J F Lechner; R R Reddel; A B Roberts; K C Robbins; E W Gabrielson; C C Harris
Journal:  Cancer Res       Date:  1987-12-01       Impact factor: 12.701

4.  Purification and cryopreservation of phagocytes from human blood.

Authors:  D Roos; M de Boer
Journal:  Methods Enzymol       Date:  1986       Impact factor: 1.600

5.  Permselectivity of the peritoneum to neutral dextrans.

Authors:  P Hirszel; E K Chakrabarti; R R Bennett; J F Maher
Journal:  Trans Am Soc Artif Intern Organs       Date:  1984

Review 6.  Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

Authors:  M Baggiolini; A Walz; S L Kunkel
Journal:  J Clin Invest       Date:  1989-10       Impact factor: 14.808

7.  CA 125 secretion by peritoneal mesothelial cells.

Authors:  A M Zeillemaker; H A Verbrugh; A A Hoynck van Papendrecht; P Leguit
Journal:  J Clin Pathol       Date:  1994-03       Impact factor: 3.411

8.  Regulation of the cytoskeleton in mesothelial cells: reversible loss of keratin and increase in vimentin during rapid growth in culture.

Authors:  N D Connell; J G Rheinwald
Journal:  Cell       Date:  1983-08       Impact factor: 41.582

9.  A three-dimensional model system to study the interactions between human leukocytes and endothelial cells.

Authors:  B C Hakkert; J M Rentenaar; W G Van Aken; D Roos; J A Van Mourik
Journal:  Eur J Immunol       Date:  1990-12       Impact factor: 5.532

10.  The effect of neutrophil migration on epithelial permeability.

Authors:  L C Milks; G P Conyers; E B Cramer
Journal:  J Cell Biol       Date:  1986-12       Impact factor: 10.539
View more
  10 in total

1.  TNF-α induces vectorial secretion of IL-8 in Caco-2 cells.

Authors:  Dennis I Sonnier; Stephanie R Bailey; Rebecca M Schuster; Alex B Lentsch; Timothy A Pritts
Journal:  J Gastrointest Surg       Date:  2010-09-09       Impact factor: 3.452

2.  Increased matrix metalloproteinase-9 activity in human ovarian cancer cells cultured with conditioned medium from human peritoneal tissue.

Authors:  K Shibata; F Kikkawa; A Nawa; K Tamakoshi; N Suganuma; Y Tomoda
Journal:  Clin Exp Metastasis       Date:  1997-11       Impact factor: 5.150

3.  Limited influence of the mesothelium on the influx of monocytes into the peritoneal cavity.

Authors:  A M Zeillemaker; F P Mul; A A Van Papendrecht; P Leguit; H A Verbrugh; D Roos
Journal:  Inflammation       Date:  1996-02       Impact factor: 4.092

4.  Polarized secretion of IL-6 and IL-8 by human retinal pigment epithelial cells.

Authors:  G M Holtkamp; M Van Rossem; A F de Vos; B Willekens; R Peek; A Kijlstra
Journal:  Clin Exp Immunol       Date:  1998-04       Impact factor: 4.330

5.  Synthesis of C-X-C and C-C chemokines by human peritoneal fibroblasts: induction by macrophage-derived cytokines.

Authors:  J Witowski; A Thiel; R Dechend; K Dunkel; N Fouquet; T O Bender; J M Langrehr; G M Gahl; U Frei; A Jörres
Journal:  Am J Pathol       Date:  2001-04       Impact factor: 4.307

6.  Mononuclear leucocyte function tests in the assessment of the biocompatibility of peritoneal dialysis fluids.

Authors:  H F Brulez; P M ter Wee; S V Snijders; A J Donker; H A Verbrugh
Journal:  J Clin Pathol       Date:  1999-12       Impact factor: 3.411

7.  Polarized secretion of interleukin (IL)-6 and IL-8 by human airway epithelia 16HBE14o- cells in response to cationic polypeptide challenge.

Authors:  Alison Wai-ming Chow; Jocelyn Feng-ting Liang; Janice Siu-chong Wong; Yan Fu; Nelson Leung-sang Tang; Wing-hung Ko
Journal:  PLoS One       Date:  2010-08-12       Impact factor: 3.240

8.  Transforming growth factor-beta synthesis by human peritoneal mesothelial cells. Induction by interleukin-1.

Authors:  F A Offner; H Feichtinger; S Stadlmann; P Obrist; C Marth; P Klingler; B Grage; M Schmahl; C Knabbe
Journal:  Am J Pathol       Date:  1996-05       Impact factor: 4.307

9.  In vitro Intestinal Mucosal Epithelial Responses to Wild-Type Salmonella Typhi and Attenuated Typhoid Vaccines.

Authors:  Maria Fiorentino; Karen M Lammers; Myron M Levine; Marcelo B Sztein; Alessio Fasano
Journal:  Front Immunol       Date:  2013-02-12       Impact factor: 7.561

10.  Patterns for RANTES secretion and intercellular adhesion molecule 1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo.

Authors:  M Taguchi; D Sampath; T Koga; M Castro; D C Look; S Nakajima; M J Holtzman
Journal:  J Exp Med       Date:  1998-06-15       Impact factor: 14.307
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.