| Literature DB >> 7748984 |
T L Strickland1, K M Lin, P Fu, D Anderson, Y Zheng.
Abstract
Lithium RBC/plasma ratio (LR) was studied in 34 bipolar subjects on therapeutic doses of lithium carbonate. The sample was divided into 22 Caucasians and 12 African-Americans to observe possible ethnic differences in LR as previously reported. The latter group demonstrated a higher LR as well as increased reports of side effects (p < .05), even after controlling previous confounding factors. Our findings suggest that African-Americans may be more susceptible to the side effects associated with lithium treatment, and consequently, lower dosages may be necessary for this group.Entities:
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Year: 1995 PMID： 7748984 DOI： 10.1016/0006-3223(94)00133-N
Source DB: PubMed Journal: Biol Psychiatry ISSN： 0006-3223 Impact factor: 13.382