Literature DB >> 7748129

32 cases of sympathetic ophthalmia. A retrospective study at the National Eye Institute, Bethesda, Md., from 1982 to 1992.

C C Chan1, R G Roberge, S M Whitcup, R B Nussenblatt.   

Abstract

OBJECTIVE: To examine the relationship between visual outcome and the clinical management of patients with sympathetic ophthalmia.
METHODS: Thirty-two patients with sympathetic ophthalmia who were seen at the National Eye Institute, Bethesda, Md, between 1982 and 1992, were retrospectively reviewed.
RESULTS: There were equal numbers of males and females. Sympathetic ophthalmia occurred after trauma in 23 patients and surgery in nine patients. Sixteen of the 32 patients had a final visual acuity of 20/40 or better; 10 patients had a visual acuity worse than 20/200. Good visual outcome was associated with early and aggressive treatment with corticosteroids, sometimes in combination with other immunosuppressive agents. Poor visual acuity was associated with glaucoma, chorioretinal scars in the macula, and persistent uncontrolled inflammation.
CONCLUSION: Prompt and aggressive use of antiinflammatory therapy can improve the visual outcome of patients with sympathetic ophthalmia.

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Year:  1995        PMID: 7748129     DOI: 10.1001/archopht.1995.01100050065032

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  29 in total

1.  Prospective surveillance of sympathetic ophthalmia in the UK and Republic of Ireland.

Authors:  D J Kilmartin; A D Dick; J V Forrester
Journal:  Br J Ophthalmol       Date:  2000-03       Impact factor: 4.638

Review 2.  Penetrating ocular injuries in previously injured blind eyes: should we consider primary enucleation?

Authors:  D A Hollander; B H Jeng; J M Stewart
Journal:  Br J Ophthalmol       Date:  2004-03       Impact factor: 4.638

3.  Inflammatory cytokine and chemokine expression in sympathetic ophthalmia: a pilot study.

Authors:  Emiko Furusato; DeFen Shen; Xiaoguang Cao; Bungo Furusato; Robert B Nussenblatt; Elisabeth J Rushing; Chi-Chao Chan
Journal:  Histol Histopathol       Date:  2011-09       Impact factor: 2.303

Review 4.  The role of sex in uveitis and ocular inflammation.

Authors:  Ian Y L Yeung; Nicholas A Popp; Chi-Chao Chan
Journal:  Int Ophthalmol Clin       Date:  2015

Review 5.  Gender disparities in ocular inflammatory disorders.

Authors:  Hatice Nida Sen; Janet Davis; Didar Ucar; Austin Fox; Chi Chao Chan; Debra A Goldstein
Journal:  Curr Eye Res       Date:  2014-07-02       Impact factor: 2.424

6.  Postsurgical sympathetic ophthalmia: retrospective analysis of a rare entity.

Authors:  Parthopratim Dutta Majumder; Eliza Anthony; Amala Elizabeth George; Sudha K Ganesh; Jyotirmay Biswas
Journal:  Int Ophthalmol       Date:  2017-11-21       Impact factor: 2.031

7.  Outcomes of ocular evisceration and enucleation in the British Armed Forces from Iraq and Afghanistan.

Authors:  Christopher J Holmes; Anthony McLaughlin; Tahir Farooq; John Awad; Aidan Murray; Robert Scott
Journal:  Eye (Lond)       Date:  2019-06-05       Impact factor: 3.775

8.  Immunogenetics and clinical phenotype of sympathetic ophthalmia in British and Irish patients.

Authors:  D J Kilmartin; D Wilson; J Liversidge; A D Dick; J Bruce; R W Acheson; S J Urbaniak; J V Forrester
Journal:  Br J Ophthalmol       Date:  2001-03       Impact factor: 4.638

9.  Sympathetic ophthalmia: what have we learned?

Authors:  H Nida Sen; Robert B Nussenblatt
Journal:  Am J Ophthalmol       Date:  2009-11       Impact factor: 5.258

Review 10.  Sympathetic ophthalmia.

Authors:  Claudia Patricia Castiblanco; Ron A Adelman
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-09-16       Impact factor: 3.117

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