Literature DB >> 7747100

Long-term remission of Kaposi's sarcoma following foscarnet treatment in HIV-infected patients.

L Morfeldt1, J Torssander.   

Abstract

Five patients with HIV-associated Kaposi's sarcoma (epidemic KS) were treated with foscarnet 180 mg/kg/day i.v. for 10 days. Four of them suffered from severe immunodeficiency with CD4 cell counts below 30 x 10(6)/l. Three of the patients went into long-term remission of KS. One patient was free of relapse for 12 months and 2 patients are still in remission after an observation period of 13 and 20 months respectively. The results suggest a possible role of foscarnet in the treatment of epidemic KS.

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Year:  1994        PMID： 7747100     DOI： 10.3109/00365549409008645

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN： 0036-5548


  16 in total

1.  Alpha interferon inhibits human herpesvirus 8 (HHV-8) reactivation in primary effusion lymphoma cells and reduces HHV-8 load in cultured peripheral blood mononuclear cells.

Authors:  P Monini; F Carlini; M Stürzl; P Rimessi; F Superti; M Franco; G Melucci-Vigo; A Cafaro; D Goletti; C Sgadari; S Butto'; P Leone; C Chiozzini; C Barresi; A Tinari; A Bonaccorsi; M R Capobianchi; M Giuliani; A di Carlo; M Andreoni; G Rezza; B Ensoli
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

2.  Recent aspects of HIV and HIV-related diseases.

Authors:  L Gürtler
Journal:  Infection       Date:  1997 Mar-Apr       Impact factor: 3.553

3.  AIDS and non AIDS-related malignant lymphoma in Tanzania.

Authors:  Ephata E Kaaya; Esmeralda Castaños-Velez; Marianne Ekman; Amos Mwakigonja; Primo Carneiro; Leonard Lema; James Kitinya; Anika Linde; Peter Biberfeld
Journal:  Afr Health Sci       Date:  2006-06       Impact factor: 0.927

4.  Kaposi's sarcoma of the pancreas mimicking pancreatic cancer in an HIV-infected patient. Clinical diagnosis by detection of HHV 8 in bile and complete remission following antiviral and cytostatic therapy with paclitaxel.

Authors:  M Menges; H W Pees
Journal:  Int J Pancreatol       Date:  1999-12

Review 5.  Human herpesvirus 8-associated neoplasms: the roles of viral replication and antiviral treatment.

Authors:  Soren Gantt; Corey Casper
Journal:  Curr Opin Infect Dis       Date:  2011-08       Impact factor: 4.915

Review 6.  Charting a new course through the chaos of KS (Kaposi's sarcoma)

Authors:  B J Nickoloff; K E Foreman
Journal:  Am J Pathol       Date:  1996-05       Impact factor: 4.307

7.  Pilot study of oral valganciclovir therapy in patients with classic Kaposi sarcoma.

Authors:  Susan E Krown; Dirk P Dittmer; Ethel Cesarman
Journal:  J Infect Dis       Date:  2011-04-15       Impact factor: 5.226

8.  Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy.

Authors:  D H Kedes; D Ganem
Journal:  J Clin Invest       Date:  1997-05-01       Impact factor: 14.808

Review 9.  A risk and benefit assessment of treatment for AIDS-related Kaposi's sarcoma.

Authors:  G Nasti; D Errante; S Santarossa; E Vaccher; U Tirelli
Journal:  Drug Saf       Date:  1999-05       Impact factor: 5.606

10.  Chromatin remodeling of the Kaposi's sarcoma-associated herpesvirus ORF50 promoter correlates with reactivation from latency.

Authors:  Fang Lu; Jing Zhou; Andreas Wiedmer; Kevin Madden; Yan Yuan; Paul M Lieberman
Journal:  J Virol       Date:  2003-11       Impact factor: 5.103
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