Literature DB >> 7745717

Cytopathogenicity of classical swine fever virus caused by defective interfering particles.

G Meyers1, H J Thiel.   

Abstract

For three independent cytopathogenic isolates of classical swine fever virus, defective RNAs were found in infected cells in addition to full-length viral genomes. These RNAs represent the genomes of typical defective interfering (DI) particles because of strict dependence on a complementing helper virus and interference with the replication of the helper virus. Analysis of the DI genomes revealed internal deletions of 4,764 nucleotides encompassing the complete structural protein-coding region of the virus and two flanking nonstructural genes. Plaque isolation and RNA transfection experiments showed that the DI particles are responsible for the cytopathic effect caused by these classical swine fever virus isolates.

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Year:  1995        PMID： 7745717      PMCID： PMC189084          DOI： 10.1128/JVI.69.6.3683-3689.1995

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  36 in total

1.  Ubiquitin in a togavirus.

Authors:  G Meyers; T Rümenapf; H J Thiel
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Review 2.  Bovine viral diarrhea virus: a review.

Authors:  J C Baker
Journal:  J Am Vet Med Assoc       Date:  1987-06-01       Impact factor: 1.936

3.  Synthesis of infectious poliovirus RNA by purified T7 RNA polymerase.

Authors:  S van der Werf; J Bradley; E Wimmer; F W Studier; J J Dunn
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

Review 4.  Defective interfering viruses and infections of animals.

Authors:  A D Barrett; N J Dimmock
Journal:  Curr Top Microbiol Immunol       Date:  1986       Impact factor: 4.291

5.  The coding region for the 54-kDa protein of several pestiviruses lacks host insertions but reveals a "zinc finger-like" domain.

Authors:  L De Moerlooze; M Desport; A Renard; C Lecomte; J Brownlie; J A Martial
Journal:  Virology       Date:  1990-08       Impact factor: 3.616

6.  Hog cholera virus--characterization of specific antiserum and identification of cDNA clones.

Authors:  T Rümenapf; G Meyers; R Stark; H J Thiel
Journal:  Virology       Date:  1989-07       Impact factor: 3.616

7.  Molecular cloning and nucleotide sequence of the genome of hog cholera virus.

Authors:  G Meyers; T Rümenapf; H J Thiel
Journal:  Virology       Date:  1989-08       Impact factor: 3.616

8.  Monoclonal antibody analyses of cytopathic and noncytopathic viruses from fatal bovine viral diarrhea virus infections.

Authors:  W V Corapi; R O Donis; E J Dubovi
Journal:  J Virol       Date:  1988-08       Impact factor: 5.103

9.  Proteins encoded by bovine viral diarrhea virus: the genomic organization of a pestivirus.

Authors:  M S Collett; R Larson; S K Belzer; E Retzel
Journal:  Virology       Date:  1988-07       Impact factor: 3.616

10.  Pestivirus glycoprotein which induces neutralizing antibodies forms part of a disulfide-linked heterodimer.

Authors:  E Weiland; R Stark; B Haas; T Rümenapf; G Meyers; H J Thiel
Journal:  J Virol       Date:  1990-08       Impact factor: 5.103
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  33 in total

1.  Phylogenetic comparison and molecular epidemiology of classical swine fever virus.

Authors:  H Björklund; P Lowings; T Stadejek; S Vilcek; I Greiser-Wilke; D Paton; S Belák
Journal:  Virus Genes       Date:  1999       Impact factor: 2.332

2.  Classical swine fever virus E(rns) deletion mutants: trans-complementation and potential use as nontransmissible, modified, live-attenuated marker vaccines.

Authors:  M N Widjojoatmodjo; H G van Gennip; A Bouma; P A van Rijn; R J Moormann
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

3.  Experimental evolution of complexity: in vitro emergence of intermolecular ribozyme interactions.

Authors:  M M Hanczyc; R L Dorit
Journal:  RNA       Date:  1998-03       Impact factor: 4.942

4.  Serine protease of pestiviruses: determination of cleavage sites.

Authors:  N Tautz; K Elbers; D Stoll; G Meyers; H J Thiel
Journal:  J Virol       Date:  1997-07       Impact factor: 5.103

5.  RNA recombination between persisting pestivirus and a vaccine strain: generation of cytopathogenic virus and induction of lethal disease.

Authors:  P Becher; M Orlich; H J Thiel
Journal:  J Virol       Date:  2001-07       Impact factor: 5.103

6.  Infectious bovine viral diarrhea virus (strain NADL) RNA from stable cDNA clones: a cellular insert determines NS3 production and viral cytopathogenicity.

Authors:  E Mendez; N Ruggli; M S Collett; C M Rice
Journal:  J Virol       Date:  1998-06       Impact factor: 5.103

7.  Characterization of cytopathogenicity of classical swine fever virus isolate induced by Newcastle disease virus.

Authors:  S D Raut; K K Rajak; R Kumar; V K Singh; A Saxena; D Chaudhary; D Muthuchelvan; A B Pandey
Journal:  Virusdisease       Date:  2015-05-23

8.  Nucleotide sequence of classical swine fever virus strain Alfort/187 and transcription of infectious RNA from stably cloned full-length cDNA.

Authors:  N Ruggli; J D Tratschin; C Mittelholzer; M A Hofmann
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

9.  High levels of subgenomic HCV plasma RNA in immunosilent infections.

Authors:  Flavien Bernardin; Susan L Stramer; Barbara Rehermann; Kimberly Page-Shafer; Stewart Cooper; David R Bangsberg; Judith Hahn; Leslie Tobler; Michael Busch; Eric Delwart
Journal:  Virology       Date:  2007-05-09       Impact factor: 3.616

10.  Processing of a pestivirus protein by a cellular protease specific for light chain 3 of microtubule-associated proteins.

Authors:  Jens Fricke; Christiane Voss; Michael Thumm; Gregor Meyers
Journal:  J Virol       Date:  2004-06       Impact factor: 5.103
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