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Literature DB >> 7742370

Molecular cloning and expression of human ribonuclease 4 cDNA.

M Seno¹, J Futami, Y Tsushima, K Akutagawa, M Kosaka, H Tada, H Yamada.

Abstract

A cDNA coding for human ribonuclease 4 was isolated from a pancreas cDNA library and sequenced. This cDNA (996 bp) includes an entire open reading frame encoding mature protein (119 aa) following signal peptide (28 aa). Expression of mature protein in Escherichia coli showed an apparent molecular mass of about 16 kDa, which was slightly lower than the mature form of human RNase 1, in SDS-PAGE.

Entities: Chemical Gene Species

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Year: 1995 PMID： 7742370 DOI： 10.1016/0167-4781(95)00040-n

Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002

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Cited

10 in total

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Authors: Kimberly D Dyer; Helene F Rosenberg
Journal: Mol Divers Date: 2006-11 Impact factor: 2.943

2. Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the ribonuclease A gene family.

Authors: D Batten; K D Dyer; J B Domachowske; H F Rosenberg
Journal: Nucleic Acids Res Date: 1997-11-01 Impact factor: 16.971

3. Ribonuclease 4 is associated with aggressiveness and progression of prostate cancer.

Authors: Nil Vanli; Jinghao Sheng; Shuping Li; Zhengping Xu; Guo-Fu Hu
Journal: Commun Biol Date: 2022-06-25

4. Human ribonuclease 4 (RNase 4): coding sequence, chromosomal localization and identification of two distinct transcripts in human somatic tissues.

Authors: H F Rosenberg; K D Dyer
Journal: Nucleic Acids Res Date: 1995-11-11 Impact factor: 16.971

Molecular cloning and expression of human ribonuclease 4 cDNA.

Review 1. The RNase a superfamily: generation of diversity and innate host defense.

2. Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the ribonuclease A gene family.

3. Ribonuclease 4 is associated with aggressiveness and progression of prostate cancer.

4. Human ribonuclease 4 (RNase 4): coding sequence, chromosomal localization and identification of two distinct transcripts in human somatic tissues.

5. Expression and function of human ribonuclease 4 in the kidney and urinary tract.

6. The mouse RNase 4 and RNase 5/ang 1 locus utilizes dual promoters for tissue-specific expression.

7. mRNA N6-methyladenosine methylation of postnatal liver development in pig.

Review 8. The Immunomodulatory and Antimicrobial Properties of the Vertebrate Ribonuclease A Superfamily.

Review 9. The Responses of the Ribonuclease A Superfamily to Urinary Tract Infection.

10. In silico prediction and in vitro characterization of multifunctional human RNase3.