Literature DB >> 7739791

Linkage between brain serotonin concentration and the sex-specific part of the Y-chromosome in mice.

S Tordjman1, P L Roubertoux, M Carlier, R Moutier, G Anderson, M Launay, H Degrelle.   

Abstract

The implication of the sex-specific part of the Y-chromosome (YS-SP) on brain serotonin (5-HT) level was investigated using congenic strains for this chromosomal region. The 5-HT level, which was higher in the NZB than in the CBA/H strain of mice, was depleted by the transfer of the YS-SP from NZB on CBA/H whereas the transfer of the YS-SP from CBA/H on NZB had no effect. The variations of 5-HT levels were not correlated with plasma testosterone concentration which is also dependent of the YS-SP.

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Year:  1995        PMID: 7739791     DOI: 10.1016/0304-3940(94)11148-c

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  7 in total

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7.  Sex genes for genomic analysis in human brain: internal controls for comparison of probe level data extraction.

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  7 in total

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