Literature DB >> 7738743

Cost per anomaly: what does a diaphragmatic hernia cost?

A P Metkus1, L Esserman, A Sola, M R Harrison, N S Adzick.   

Abstract

The cost of medical care in the United States is under close scrutiny. Birth defects have surpassed prematurity as the leading cause of infant mortality in the United States and contribute significantly to infant morbidity. Few estimates have been made of the costs of individual birth defects. The authors sought to determine the cost of initial hospitalization for an infant with a congenital diaphragmatic hernia (CDH). They analyzed hospital bills and professional fees from all 35 cases of infants who underwent postnatal CDH repair at their institution between January 1990 and December 1993. The cost averaged $137,000 per patient, and ECMO dramatically increased the cost. The cost per survivor was $98,000 in the non-ECMO group and $365,000 in the ECMO group. The estimated cost of CDH per year in the United States is more than $230 million. This study suggests several strategies for cost reduction, provides data for future cost comparisons, and serves as a cost comparison for evaluating new therapeutic strategies for CDH.

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Year:  1995        PMID: 7738743     DOI: 10.1016/0022-3468(95)90565-0

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  7 in total

1.  Increased burden of de novo predicted deleterious variants in complex congenital diaphragmatic hernia.

Authors:  Lan Yu; Ashley D Sawle; Julia Wynn; Gudrun Aspelund; Charles J Stolar; Marc S Arkovitz; Douglas Potoka; Kenneth S Azarow; George B Mychaliska; Yufeng Shen; Wendy K Chung
Journal:  Hum Mol Genet       Date:  2015-06-01       Impact factor: 6.150

2.  Cost of neonatal intensive care.

Authors:  R Shanmugasundaram; E Padmapriya; J Shyamala
Journal:  Indian J Pediatr       Date:  1998 Mar-Apr       Impact factor: 1.967

3.  Germline but not somatic de novo mutations are common in human congenital diaphragmatic hernia.

Authors:  Nori Matsunami; Hari Shanmugam; Lisa Baird; Jeff Stevens; Janice L Byrne; Douglas C Barnhart; Carrie Rau; Marcia L Feldkamp; Bradley A Yoder; Mark F Leppert; H Joseph Yost; Luca Brunelli
Journal:  Birth Defects Res       Date:  2018-03-23       Impact factor: 2.344

Review 4.  Advances in fetal surgery.

Authors:  Kathryn M Maselli; Andrea Badillo
Journal:  Ann Transl Med       Date:  2016-10

5.  Prenatal glucocorticoid therapy reverses pulmonary immaturity in congenital diaphragmatic hernia in fetal sheep.

Authors:  J J Schnitzer; H L Hedrick; B A Pacheco; P D Losty; D P Ryan; D P Doody; P K Donahoe
Journal:  Ann Surg       Date:  1996-10       Impact factor: 12.969

6.  Role of catalytic iron and oxidative stress in nitrofen-induced congenital diaphragmatic hernia and its amelioration by Saireito (TJ-114).

Authors:  Shima Hirako; Hiroyuki Tsuda; Fumiya Ito; Yasumasa Okazaki; Tasuku Hirayama; Hideko Nagasawa; Tomoko Nakano; Kenji Imai; Tomomi Kotani; Fumitaka Kikkawa; Shinya Toyokuni
Journal:  J Clin Biochem Nutr       Date:  2017-09-05       Impact factor: 3.114

7.  Antenatal sildenafil administration to prevent pulmonary hypertension in congenital diaphragmatic hernia (SToP-PH): study protocol for a phase I/IIb placenta transfer and safety study.

Authors:  Francesca Maria Russo; Alexandra Benachi; Tim Van Mieghem; Jan De Hoon; Kristel Van Calsteren; Pieter Annaert; Jean-Marc Tréluyer; Karel Allegaert; Jan Deprest
Journal:  Trials       Date:  2018-09-27       Impact factor: 2.279

  7 in total

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