| Literature DB >> 7738729 |
M M Albert1, K Adams, M J Luther, S H Sun, J R Graybill.
Abstract
ICR mice were infected intranasally with arthroconidia of Coccicioides immitis. Mice were treated intravenously with amphotericin B deoxycholate (Fungizone) or an amphotericin B-lipid vehicle (AmBisome). Doses ranged from 0.05 to 1.0 mg kg-1. Lung weight, which parallels disease severity and fungal burden in this infection, was used as the index of protection. Both Fungizone and AmBisome were significantly and equally protective at 0.3 and 1.0 mg kg-1 body weight.Entities:
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Year: 1994 PMID： 7738729 DOI： 10.1080/02681219480000621
Source DB: PubMed Journal: J Med Vet Mycol ISSN： 0268-1218