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Literature DB >> 773789

Induction of pyloric hypertrophy by pentagastrin. An animal model for infantile hypertrophic pyloric stenosis.

Abstract

Administration of pentagastrin in depot form to 20 pregnant bitches produced pyloric hypertrophy in about 28% and gastroduodenal ulceration in about 16% of their pups. The two lesions were not necessarily found in the same individuals. Histological appearances of the pylorus in affected pups closely resembled those of human infantile pyloric stenosis.

Entities: Chemical Disease Species

Mesh：

Substances：
Pentagastrin

Year: 1976 PMID： 773789 PMCID： PMC1411097 DOI： 10.1136/gut.17.4.280

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

7 in total

1. Neonatal secretion of gastrin and glucagon.

Authors: I M Rogers; D C Davidson; J Lawrence; J Ardill; K D Buchanan
Journal: Arch Dis Child Date: 1974-10 Impact factor: 3.791

2. Gastrointestinal motility and gastric secretion during intravenous infusions of gastrin II.

Authors: J J Misiewicz; S L Waller; D J Holdstock
Journal: Gut Date: 1969-09 Impact factor: 23.059

3. Gastric secretion in the canine fetus following maternal stimulation: experimental studies on placental transfer of insulin, histamine, and gastrin.

Authors: W L Bruckner; H D Snow; E W Fonkalsrud
Journal: Surgery Date: 1970-02 Impact factor: 3.982

4. Production of duodenal ulcers and hypertrophic pyloric stenosis by administration of pentagastrin to pregnant and newborn dogs.

Authors: J A Dodge
Journal: Nature Date: 1970-01-17 Impact factor: 49.962

5. Hypertrophic pyloric stenosis at the Children's Hospital of Pittsburgh from 1912 to 1967. A critical review of current problems and complications.

Authors: A Schärli; W K Sieber; W B Kiesewetter
Journal: J Pediatr Surg Date: 1969-02 Impact factor: 2.545

6. Pentagastrin-induced stimulation of protein synthesis in the gastrointestinal tract.

Authors: L R Johnson; D Aures; L Yuen
Journal: Am J Physiol Date: 1969-07

7. [The so-called pylorus hypertrophy in animal experiments].

Authors: H M Heinisch
Journal: Klin Wochenschr Date: 1967-12-15

7 in total

13 in total

Review 1. Infantile hypertrophic pyloric stenosis--genetics and syndromes.

Authors: Babette Peeters; Marc A Benninga; Raoul C M Hennekam
Journal: Nat Rev Gastroenterol Hepatol Date: 2012-07-10 Impact factor: 46.802

2. Hunterian Lecture. The ontogeny of the peptide innervation of the human pylorus with special reference to understanding the aetiology and pathogenesis of infantile hypertrophic pyloric stenosis.

Authors: R M Abel
Journal: Ann R Coll Surg Engl Date: 2000-11 Impact factor: 1.891

Induction of pyloric hypertrophy by pentagastrin. An animal model for infantile hypertrophic pyloric stenosis.

1. Neonatal secretion of gastrin and glucagon.

2. Gastrointestinal motility and gastric secretion during intravenous infusions of gastrin II.

3. Gastric secretion in the canine fetus following maternal stimulation: experimental studies on placental transfer of insulin, histamine, and gastrin.

4. Production of duodenal ulcers and hypertrophic pyloric stenosis by administration of pentagastrin to pregnant and newborn dogs.

5. Hypertrophic pyloric stenosis at the Children's Hospital of Pittsburgh from 1912 to 1967. A critical review of current problems and complications.

6. Pentagastrin-induced stimulation of protein synthesis in the gastrointestinal tract.

7. [The so-called pylorus hypertrophy in animal experiments].

Review 1. Infantile hypertrophic pyloric stenosis--genetics and syndromes.

2. Hunterian Lecture. The ontogeny of the peptide innervation of the human pylorus with special reference to understanding the aetiology and pathogenesis of infantile hypertrophic pyloric stenosis.

Review 3. Pyloric stenosis: an enigma more than a century after the first successful treatment.

4. Conservative management of infantile pyloric stenosis by nasoduodenal feeding.

5. Increased serum immunoreactive gastrin levels in idiopathic hypertrophic pyloric stenosis.

6. Is maternal gastrin important in congenital hypertrophic pyloric stenosis?

Review 7. The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental?

8. Infantile hypertrophic pyloric stenosis in South Glamorgan 1970-9. Effects of changes in feeding practice.

9. Changes in gastric myoelectrical activity in hypertrophic pyloric stenosis and after surgical correction.

10. Infantile hypertrophic pyloric stenosis after prenatal exposure to thalidomide.