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Literature DB >> 773788

Continuous monitoring of the effect of pentagastrin on gastric emptying of solid food in man.

Abstract

By continuous monitoring of a solid meal labelled with a radiopharmaceutical it has been possible to determine the effects of drugs on gastric emptying and motility during a single study. Predictably hyoscine delayed, and bethanechol increased, the rate of gastric emptying. Pentagastrin initially produced marked antral activity resulting in a physiological stricture and subsequent delay in the overall rate of gastric emptying. Fundal motility was unaffected though reflux from the antrum occurred.

Entities: Chemical Species

Mesh：

Substances：
Technetium
Pentagastrin

Year: 1976 PMID： 773788 PMCID： PMC1411107 DOI： 10.1136/gut.17.4.273

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

25 in total

Continuous monitoring of the effect of pentagastrin on gastric emptying of solid food in man.

1. The pattern of emptying of the human stomach.

2. Effect of gastrin on isolated smooth muscle preparation.

3. Measurement of rate of gastric emptying using chromium-51.

4. Effects of gastrin and its analogues on isolated smooth muscles.

5. Measurement of gastric emptying time with a gamma camera.

6. Use of 99mTc-DTPA for measuring gastric emptying time.

7. Effect of pentagastrin on emptying and electrical and motor activity of the dog stomach.

8. Effect of gastrin on gastric myo-electric activity.

9. Supersensitivity and gastric emptying after vagotomy.

10. Analysis of the motor effects of gastrin and pentagastrin on the human alimentary tract in vitro.

1. Effect of coffee on motor and sensory function of proximal stomach.

2. Evaluation of reproducibility of solid-phase gastric emptying in healthy subjects.

Review 3. Effects of proton pump inhibitors on gastric emptying: a systematic review.

4. Effect of omeprazole 20 mg twice daily on duodenogastric and gastro-oesophageal bile reflux in Barrett's oesophagus.

5. The two-component stomach: effects of meal particle size on fundal and antral emptying.

6. Effect of pentagastrin infusion on gastric emptying rate of solid food in man.

7. Gastric motility and emptying in normal and post-vagotomy subjects.

8. Cholinergic effects on human gastric motility.

9. Effects of rabeprazole sodium on gastric emptying, electrogastrography, and fullness.

10. The effect of beta-adrenoceptor agonists and antagonists on gastric emptying in man.