Literature DB >> 7734926

Solvation of platinum anti-cancer drugs in methanol-water mixtures.

J Burgess1, D N Drasdo, M S Patel.   

Abstract

Solubilities and transfer chemical potentials of carboplatin, cisplatin, iproplatin, and several related platinum complexes have been determined in methanol-water mixtures. The range of solvation behaviour is discussed in relation to possible oral administration of complexes of this type.

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Year:  1995        PMID: 7734926     DOI: 10.1007/bf00142013

Source DB:  PubMed          Journal:  Biometals        ISSN: 0966-0844            Impact factor:   2.949


  6 in total

1.  Cosolvent effects on diuron solubility.

Authors:  L A Hardaway; S H Yalkowsky
Journal:  J Pharm Sci       Date:  1991-02       Impact factor: 3.534

2.  [Study of solubility of sulfanilamide compounds in water-ethanol mixtures].

Authors:  A I Shkadova
Journal:  Farm Zh       Date:  1969

3.  Lack of neurotoxicity of oral bisacetatoamminedichlorocyclohexylamine-platinum(IV) in comparison to cisplatin and tetraplatin in the rat.

Authors:  M J McKeage; F E Boxall; M Jones; K R Harrap
Journal:  Cancer Res       Date:  1994-02-01       Impact factor: 12.701

4.  Synthesis, antitumor activity, and nephrotoxicity of the optical isomers of 2-aminomethylpyrrolidine(1,1-cyclobutane-dicarboxylato)platinum(II).

Authors:  K Morikawa; M Honda; K Endoh; T Matsumoto; K Akamatsu; H Mitsui; M Koizumi
Journal:  J Pharm Sci       Date:  1991-09       Impact factor: 3.534

Review 5.  New platinum antitumor complexes.

Authors:  L R Kelland
Journal:  Crit Rev Oncol Hematol       Date:  1993-12       Impact factor: 6.312

6.  Solubilities and solvation of aluminum(III), iron(III), and indium(III) 8-hydroxyquinolinates in methanol/water mixtures.

Authors:  J Burgess; D N Drasdo; M S Patel
Journal:  J Pharm Sci       Date:  1994-01       Impact factor: 3.534

  6 in total

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