Literature DB >> 773401

Evidence for the multiplication of hepatitis B virus in "oval cell" culture originated from human embryonic liver.

M Watanabe, T Umenai, H Ohori, N Ishida.   

Abstract

Growth conditions fof human oval cells (immature hepatocytes),evidence of hepatitis B (HB) antigen synthesis in oval cells as revealed by immunofluorescent staining and successful passage of such an agent in the culture fluid up to the 4th passage are described. The results have been proved to be readily reproducible with different inocula. The oval cells used in these experiments were defined as small round cells, with scant cytoplasm, vesicular nuclei and small nucleoli, vitally stained with indocyanine green and synthesizing alpha-foetoprotein but no albumin.

Entities:  

Mesh:

Substances:

Year:  1976        PMID: 773401      PMCID: PMC2041115     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


  8 in total

1.  The use of indocyanine green in the measurement of hepatic blood flow and as a test of hepatic function.

Authors:  J CAESAR; S SHALDON; L CHIANDUSSI; L GUEVARA; S SHERLOCK
Journal:  Clin Sci       Date:  1961-08       Impact factor: 6.124

2.  Deoxyribonucleic acid turnover in a heterogeneous population. Life span of hepatic ductular cells.

Authors:  E RUBIN; F HUTTERER; G DANON; H POPPER
Journal:  Lab Invest       Date:  1963-06       Impact factor: 5.662

3.  Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylamino-fluorene, and 3'-methyl-4-dimethylaminoazobenzene.

Authors:  E FARBER
Journal:  Cancer Res       Date:  1956-02       Impact factor: 12.701

4.  Hepatis B virus antigen development in cultured human hepatocytes.

Authors:  W F Noyes
Journal:  Proc Soc Exp Biol Med       Date:  1973-12

5.  Demonstration of glucose 6-phosphatase activity in the oval cells of rat liver and the significance of the oval cells in azo dye carcinogenesis.

Authors:  K Ogawa; T Minase; T Onhoe
Journal:  Cancer Res       Date:  1974-12       Impact factor: 12.701

6.  Hepatocyte proliferation and alpha 1-fetoprotein in pregnant, neonatal, and partially hepatectomized rats.

Authors:  S Sell; M Nichols; F F Becker; H L Leffert
Journal:  Cancer Res       Date:  1974-04       Impact factor: 12.701

7.  The circumfusion system for multipurposeculture chambers. II. The protracted maintenance of differentiation of fetal and newborn mouse liver in vitro.

Authors:  G G Rose; M Kumegawa; M Cattoni
Journal:  J Cell Biol       Date:  1968-11       Impact factor: 10.539

8.  Australia antigen as a marker of propagation of the serum hepatitis virus in liver cultures.

Authors:  A J Zuckerman; P M Baines; J D Almeida
Journal:  Nature       Date:  1972-03-10       Impact factor: 49.962

  8 in total
  5 in total

1.  Hepatitis B virus antigens in primary hepatic carcinoma: immunofluorescent techniques on fixed liver tissue.

Authors:  A Trevisan; G Realdi; C Losi; V Ninfo; M Rugge; L Rampinelli
Journal:  J Clin Pathol       Date:  1978-12       Impact factor: 3.411

2.  Widespread presence of cytoplasmic HBcAg in hepatitis B infected liver detected by improved immunochemical methods.

Authors:  E J Gowans; C J Burrell
Journal:  J Clin Pathol       Date:  1985-04       Impact factor: 3.411

Review 3.  The hepatitis B virus and its DNA polymerase: the prototype three-D virus.

Authors:  S Z Hirschman
Journal:  Mol Cell Biochem       Date:  1979-07-15       Impact factor: 3.396

4.  An in vitro system for infection with hepatitis B virus that uses primary human fetal hepatocytes.

Authors:  T Ochiya; T Tsurimoto; K Ueda; K Okubo; M Shiozawa; K Matsubara
Journal:  Proc Natl Acad Sci U S A       Date:  1989-03       Impact factor: 11.205

5.  HBx protein promotes oval cell proliferation by up-regulation of cyclin D1 via activation of the MEK/ERK and PI3K/Akt pathways.

Authors:  Heng-Yi Wang; Sheng-Li Yang; Hui-Fang Liang; Chang-Hai Li
Journal:  Int J Mol Sci       Date:  2014-02-26       Impact factor: 5.923

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.