Literature DB >> 7733876

The complete sequence of human lens gamma s-crystallin.

J B Smith1, Z Yang, P Lin, Z Zaidi, A Abbasi, P Russell.   

Abstract

The complete sequence of human gamma s-crystallin has been determined and confirmed using a combination of MS methods, peptide sequencing and cDNA sequencing. Regions 21-35 and 102-107, which were previously assumed to be the same as the bovine sequence, differ from the bovine sequence at residues 22, 28, 31 and 104. An additional six residues were also found to be different from the original sequence determined for Pakastani lenses. Whether these differences represent errors in the original sequence or two different sequences among human lens crystallins is not yet known.

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Year:  1995        PMID: 7733876      PMCID: PMC1136663          DOI: 10.1042/bj3070407

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  6 in total

1.  The concentration and localization of heavy molecular weight aggregates in aging normal and cataractous human lenses.

Authors:  J A Jedziniak; J H Kinoshita; E M Yates; G B Benedek
Journal:  Exp Eye Res       Date:  1975-04       Impact factor: 3.467

2.  Primary structure of beta s-crystallin from human lens.

Authors:  S Zarina; A Abbasi; Z H Zaidi
Journal:  Biochem J       Date:  1992-10-15       Impact factor: 3.857

3.  Post-translational modifications of water-soluble human lens crystallins from young adults.

Authors:  L R Miesbauer; X Zhou; Z Yang; Z Yang; Y Sun; D L Smith; J B Smith
Journal:  J Biol Chem       Date:  1994-04-29       Impact factor: 5.157

4.  Identification of the major components of the high molecular weight crystallins from old human lenses.

Authors:  Z Yang; M Chamorro; D L Smith; J B Smith
Journal:  Curr Eye Res       Date:  1994-06       Impact factor: 2.424

5.  Strategy for the mass spectrometric verification and correction of the primary structures of proteins deduced from their DNA sequences.

Authors:  B W Gibson; K Biemann
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

6.  A protein sequenator.

Authors:  P Edman; G Begg
Journal:  Eur J Biochem       Date:  1967-03
  6 in total
  2 in total

Review 1.  Biophysical chemistry of the ageing eye lens.

Authors:  Nicholas J Ray
Journal:  Biophys Rev       Date:  2015-08-23

2.  Femtosecond fluorescence spectra of tryptophan in human gamma-crystallin mutants: site-dependent ultrafast quenching.

Authors:  Jianhua Xu; Jiejin Chen; Dmitri Toptygin; Olga Tcherkasskaya; Patrik Callis; Jonathan King; Ludwig Brand; Jay R Knutson
Journal:  J Am Chem Soc       Date:  2009-11-25       Impact factor: 15.419

  2 in total

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