Literature DB >> 7733722

Unoperated aortic aneurysm: a survey of 170 patients.

M J Perko1, M Nørgaard, T M Herzog, P S Olsen, T V Schroeder, G Pettersson.   

Abstract

From 1984 to 1993, 1,053 patients were admitted with aortic aneurysm (AA) and 170 (15%) were not operated on. The most frequent reason for nonoperative management was presumed technical inoperability. Survivals for patients with thoracic, thoracoabdominal, and abdominal AA were comparable. No significant differences in survival for patients with dissecting and nondissecting AA were detected. In all, 132 patients (78%) died and 78 (59%) of them died of rupture. Mean time to rupture was 1,300 +/- 8 days. Cumulative 5-year hazard of rupture for the dissecting AA was twice that of the nondissecting (p < 0.001). Hazards of rupture for type A and B dissections were comparable. Diameter of 6 cm or greater was associated with a fivefold increase in cumulative hazard of rupture (p < 0.001). Diameter of AA, incidence of renal failure, and arterial hypertension were predictive of mortality, whereas the first two variables were predictive of rupture. In conclusion, because the majority of patients in all subgroups died of rupture, all patients should be recognized as candidates for surgical treatment. Present data justify aggressive approach to the patient with AA 6 cm or more in diameter and type A dissections. The results suggest that type B dissections may have a more favorable course if operated on, but a prospective, randomized study is necessary to confirm this observation. We believe that older patients and those with a small aneurysm may benefit from early, elective operation.

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Mesh:

Year:  1995        PMID: 7733722     DOI: 10.1016/0003-4975(95)00132-5

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  15 in total

1.  Endovascular therapy for thoracic aortic aneurysms: state of the art in 2012.

Authors:  Nicolas A Brozzi; Eric E Roselli
Journal:  Curr Treat Options Cardiovasc Med       Date:  2012-04

2.  Progress and future challenges in thoracoabdominal aortic aneurysm management.

Authors:  Hazim J Safi; Anthony L Estrera; Ali Azizzadeh; Sheila Coogan; Charles C Miller
Journal:  World J Surg       Date:  2008-03       Impact factor: 3.352

3.  ECG-gated MR angiography provides better reproducibility for standard aortic measurements.

Authors:  Logan R Smith; Stephen N Darty; Elizabeth R Jenista; George L Gamoneda; David C Wendell; Clerio F Azevedo; Michele A Parker; Raymond J Kim; Han W Kim
Journal:  Eur Radiol       Date:  2021-01-06       Impact factor: 5.315

4.  Intervention on thoracic and thoracoabdominal aortic aneurysms: can the UK offer a service?

Authors:  Mark L Field; Debbie Harrington; Mohamad Bashir; Manoj Kuduvalli; Aung Oo
Journal:  J R Soc Med       Date:  2012-11       Impact factor: 5.344

5.  A novel microwave sensor to detect specific biomarkers in human cerebrospinal fluid and their relationship to cellular ischemia during thoracoabdominal aortic aneurysm repair.

Authors:  M Fok; M Bashir; H Fraser; N Strouther; A Mason
Journal:  J Med Syst       Date:  2015-02-17       Impact factor: 4.460

6.  Hybrid approach for the treatment of thoracic aortic arch aneurysm in a patient with chronic obstructive lung disease and retrosternal adhesion.

Authors:  Ki Bang Kim; Won Ho Kim; Jin Ho Choi; Jeong Hee Kim; Yu Jeong Choi; Kyung Tae Jeong; Sun Chang Park; Sahng Lee
Journal:  Korean Circ J       Date:  2011-07-30       Impact factor: 3.243

7.  Clinical and patho-anatomical factors affecting expansion of thoracic aortic aneurysms.

Authors:  R S Bonser; D Pagano; M E Lewis; S J Rooney; P Guest; P Davies; I Shimada
Journal:  Heart       Date:  2000-09       Impact factor: 5.994

Review 8.  [Management of anesthesia in endovascular interventions].

Authors:  T Rössel; R Paul; T Richter; S Ludwig; T Hofmockel; A R Heller; T Koch
Journal:  Anaesthesist       Date:  2016-12       Impact factor: 1.041

Review 9.  [Aneurysms of the thoracic and thoracoabdominal aorta].

Authors:  J Zanow; U Settmacher
Journal:  Chirurg       Date:  2014-09       Impact factor: 0.955

Review 10.  A Perspective on Natural History and Survival in Nonoperated Thoracic Aortic Aneurysm Patients.

Authors:  Mohamad Bashir; Matthew Fok; Ibrahim Hammoud; Lara Rimmer; Matthew Shaw; Mark Field; Debbie Harrington; Manoj Kuduvalli; Aung Oo
Journal:  Aorta (Stamford)       Date:  2013-08-01
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