Literature DB >> 7732790

The topographic distribution of brain atrophy in cortical Lewy body disease: comparison with Alzheimer's disease.

D M Mann1, J S Snowden.   

Abstract

The topographic distribution of brain atrophy was quantified by image analysis of fixed coronal brain slices from four patients dying with cortical Lewy body disease (CLBD) all with Alzheimer-type pathology and compared to that in four other patients of similar age and gender dying with Alzheimer's disease (AD) alone. The pattern of atrophy in CLBD (+AD) was broadly similar to that in AD alone, suggesting that tissue loss was due mostly to parallel Alzheimer-type pathological changes and that the presence of Lewy bodies in cortical and subcortical neurons contributed little, if anything, to the overall degree of atrophy.

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Year:  1995        PMID： 7732790     DOI： 10.1007/bf00296363

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  20 in total

1.  Relationships between Lewy bodies and pale bodies in Parkinson's disease.

Authors:  G E Dale; A Probst; P Luthert; J Martin; B H Anderton; P N Leigh
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

2.  Diagnosis of Alzheimer's disease.

Authors:  Z S Khachaturian
Journal:  Arch Neurol       Date:  1985-11

3.  Senile dementia of Lewy body type. A clinically and neuropathologically distinct form of Lewy body dementia in the elderly.

Authors:  R H Perry; D Irving; G Blessed; A Fairbairn; E K Perry
Journal:  J Neurol Sci       Date:  1990-02       Impact factor: 3.181

4.  A morphological analysis of senile plaques in the brains of non-demented persons of different ages using silver, immunocytochemical and lectin histochemical staining techniques.

Authors:  D M Mann; A M Brown; D Prinja; D Jones; C A Davies
Journal:  Neuropathol Appl Neurobiol       Date:  1990-02       Impact factor: 8.090

5.  The topographic distribution of brain atrophy in Huntington's disease and progressive supranuclear palsy.

Authors:  D M Mann; R Oliver; J S Snowden
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

6.  The topographic distribution of brain atrophy in frontal lobe dementia.

Authors:  D M Mann; P W South
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

7.  Quantification of beta A4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type.

Authors:  S M Gentleman; B Williams; M C Royston; R Jagoe; J Clinton; R H Perry; P G Ince; D Allsop; J M Polak; G W Roberts
Journal:  Neurosci Lett       Date:  1992-08-03       Impact factor: 3.046

8.  Alzheimer's disease and Lewy body disease: a comparative clinicopathological study.

Authors:  C F Lippa; T W Smith; J M Swearer
Journal:  Ann Neurol       Date:  1994-01       Impact factor: 10.422

Review 9.  Altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementias.

Authors:  J Q Trojanowski; M L Schmidt; R W Shin; G T Bramblett; D Rao; V M Lee
Journal:  Brain Pathol       Date:  1993-01       Impact factor: 6.508

10.  Diffuse Lewy body disease: light and electron microscopic immunocytochemistry of senile plaques.

Authors:  D W Dickson; H Crystal; L A Mattiace; Y Kress; A Schwagerl; H Ksiezak-Reding; P Davies; S H Yen
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088
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  2 in total

1.  Effect of beta-amyloid block of the fast-inactivating K+ channel on intracellular Ca2+ and excitability in a modeled neuron.

Authors:  T A Good; R M Murphy
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-24       Impact factor: 11.205

2.  A clinical role for 99mTc-HMPAO SPECT in the investigation of dementia?

Authors:  P R Talbot; J J Lloyd; J S Snowden; D Neary; H J Testa
Journal:  J Neurol Neurosurg Psychiatry       Date:  1998-03       Impact factor: 10.154
  2 in total

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