Literature DB >> 7732266

Sonographic features of portal hypertension in schistosomiasis mansoni.

R A Pinto-Silva1, W L Abrantes, C M Antunes, J R Lambertucci.   

Abstract

The diagnostic value of real-time sonography in the study of portal hypertension was assessed in 66 patients with hepatosplenic schistosomiasis mansoni, all with Symmers's fibrosis and esophageal varices. Seventy-one individuals without schistosomiasis were selected as controls. The inner diameters of the portal vessels were measured by sonography in all patients and controls: splenoportography was also performed in the schistosomal group. Intra-splenic pressure was over 30 cm of water in 44 of 60 patients with schistosomiasis. The upper limit of normality for portal vessel diameters was set through receiver operating characteristic curve at 12 mm for portal vein, 9 mm for splenic vein at splenic hilus, and 9 mm for superior mesenteric vein. The best discriminative vein for the diagnosis of portal hypertension was the splenic vein followed by the portal vein. A direct correlation was observed between the diameter of the splenic vein, measured by sonography, and the intra-splenic pressure. Except for the paraumbilical and mesenteric veins, more frequently identified by sonography, there was no statistical difference in the frequency of visualization of splanchnic vessels by sonography or splenoportography.

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Year:  1994        PMID: 7732266     DOI: 10.1590/s0036-46651994000400008

Source DB:  PubMed          Journal:  Rev Inst Med Trop Sao Paulo        ISSN: 0036-4665            Impact factor:   1.846


  3 in total

Review 1.  The WHO ultrasonography protocol for assessing hepatic morbidity due to Schistosoma mansoni. Acceptance and evolution over 12 years.

Authors:  Tarik el Scheich; Martha C Holtfreter; Hendrik Ekamp; Daman D Singh; Rodrigo Mota; Christoph Hatz; Joachim Richter
Journal:  Parasitol Res       Date:  2014-09-27       Impact factor: 2.289

2.  Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni.

Authors:  Thiago A Pereira; Guanhua Xie; Steve S Choi; Wing-Kin Syn; Izabela Voieta; Jiuyi Lu; Isaac S Chan; Marzena Swiderska; Kirsten B Amaral; Carlos M Antunes; William E Secor; Rafal P Witek; José R Lambertucci; Fausto L Pereira; Anna Mae Diehl
Journal:  Liver Int       Date:  2012-11-01       Impact factor: 5.828

3.  Propranolol Reduces Portal Vein Diameter in Schistosomal Liver Disease with Portal Hypertension: A Prospective Cohort Study.

Authors:  Edford Sinkala; Michael Vinikoor; Kanekwa Zyambo; Ellen Besa; Bright Nsokolo; Paul Kelly
Journal:  Am J Trop Med Hyg       Date:  2020-04       Impact factor: 2.345

  3 in total

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