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Literature DB >> 7730970

Structure/function studies of mammalian Na-H exchangers--an update.

C H Yun¹, C M Tse, S Nath, S L Levine, M Donowitz.

Abstract

Four mammalian Na+/H+ exchangers have recently been cloned. Despite the structural similarity, these Na+/H+ exchanger isoforms differ in kinetic characteristics and their response to external stimuli. The present review deals with the recent developments in their functional characterization and their short-term regulation.

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Year: 1995 PMID： 7730970 PMCID： PMC1334232 DOI： 10.1113/jphysiol.1995.sp020558

Source DB: PubMed Journal: J Physiol ISSN： 0022-3751 Impact factor: 5.182

42 in total

1. Kinetics and regulation of three cloned mammalian Na+/H+ exchangers stably expressed in a fibroblast cell line.

Authors: S A Levine; M H Montrose; C M Tse; M Donowitz
Journal: J Biol Chem Date: 1993-12-05 Impact factor: 5.157

2. Effect of high osmolality on Na+/H+ exchange in renal proximal tubule cells.

Authors: M Soleimani; C Bookstein; J A McAteer; Y J Hattabaugh; G L Bizal; M W Musch; M Villereal; M C Rao; R L Howard; E B Chang
Journal: J Biol Chem Date: 1994-06-03 Impact factor: 5.157

Review 3. Macromolecular crowding and confinement in cells exposed to hypertonicity.

Authors: M M Garner; M B Burg
Journal: Am J Physiol Date: 1994-04

4. NHE3: a Na+/H+ exchanger isoform of renal brush border.

Authors: D Biemesderfer; J Pizzonia; A Abu-Alfa; M Exner; R Reilly; P Igarashi; P S Aronson
Journal: Am J Physiol Date: 1993-11

5. Evidence that Na+/H+ exchanger isoforms NHE1 and NHE3 exist as stable dimers in membranes with a high degree of specificity for homodimers.

Authors: P Fafournoux; J Noël; J Pouysségur
Journal: J Biol Chem Date: 1994-01-28 Impact factor: 5.157

6. CAMP-mediated inhibition of the renal brush border membrane Na+-H+ exchanger requires a dissociable phosphoprotein cofactor.

Authors: E J Weinman; D Steplock; S Shenolikar
Journal: J Clin Invest Date: 1993-10 Impact factor: 14.808

7. Ca(2+)-dependent heat production by rat skeletal muscle in hypertonic media depends on Na(+)-Cl- co-transport stimulation.

Authors: A Chinet
Journal: J Physiol Date: 1993-02 Impact factor: 5.182

8. Functional characteristics of a cloned epithelial Na+/H+ exchanger (NHE3): resistance to amiloride and inhibition by protein kinase C.

Authors: C M Tse; S A Levine; C H Yun; S R Brant; J Pouyssegur; M H Montrose; M Donowitz
Journal: Proc Natl Acad Sci U S A Date: 1993-10-01 Impact factor: 11.205

9. ATP dependence of NHE-1, the ubiquitous isoform of the Na+/H+ antiporter. Analysis of phosphorylation and subcellular localization.

Authors: G G Goss; M Woodside; S Wakabayashi; J Pouyssegur; T Waddell; G P Downey; S Grinstein
Journal: J Biol Chem Date: 1994-03-25 Impact factor: 5.157

10. Growth factor activation and "H(+)-sensing" of the Na+/H+ exchanger isoform 1 (NHE1). Evidence for an additional mechanism not requiring direct phosphorylation.

Authors: S Wakabayashi; B Bertrand; M Shigekawa; P Fafournoux; J Pouysségur
Journal: J Biol Chem Date: 1994-02-25 Impact factor: 5.157

4 in total

1. Luminal hyperosmolarity decreases Na transport and impairs barrier function of sheep rumen epithelium.

Authors: Monika Schweigel; Markus Freyer; Sabine Leclercq; Benjamin Etschmann; Ulrike Lodemann; Almut Böttcher; Holger Martens
Journal: J Comp Physiol B Date: 2005-11-11 Impact factor: 2.200

2. Cell cycle progression in monkey cells expressing simian virus 40 small t antigen from adenovirus vectors.

Authors: A K Howe; S Gaillard; J S Bennett; K Rundell
Journal: J Virol Date: 1998-12 Impact factor: 5.103

3. Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells.

Authors: Kristine A Holthouser; Amritlal Mandal; Michael L Merchant; Jeffrey R Schelling; Nicholas A Delamere; Ronald R Valdes; Suresh C Tyagi; Eleanor D Lederer; Syed J Khundmiri
Journal: Am J Physiol Renal Physiol Date: 2010-04-28

Review 4. Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.

Authors: Rongbao Zhao; Larry H Matherly; I David Goldman
Journal: Expert Rev Mol Med Date: 2009-01-28 Impact factor: 5.600

4 in total