| Literature DB >> 7729602 |
D Tannahill1, S Bray, W A Harris.
Abstract
A Drosophila Enhancer of split [E(spl)] bHLH protein, m delta, was misexpressed in Xenopus embryos along with green fluorescent protein (GFP) as a lineage label. The Drosophila protein translocated to the nucleus of Xenopus cells and led to neural hypertrophy in the GFP-labeled dorsal ectoderm, a phenotype similar to that caused by the misexpression of activated Xotch. Our data indicate a strong conservation in E(spl)bHLH function in the Notch signaling pathway of flies and vertebrates.Entities:
Mesh:
Year: 1995 PMID: 7729602 DOI: 10.1006/dbio.1995.1116
Source DB: PubMed Journal: Dev Biol ISSN: 0012-1606 Impact factor: 3.582