Literature DB >> 7727466

Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass.

M C Oz1, J P Slater, N Edwards, M L Dickstein, J R Beck, H M Spotnitz, H R Levin.   

Abstract

BACKGROUND: Right-sided circulatory failure is a major cause of morbidity in heart transplant and ventricular assist device recipients.
METHODS: Several systems for managing right-sided circulatory failure with use of a right-to-left shunt without need for an oxygenator or systemic heparinization were designed and used clinically.
RESULTS: A right-to-left shunt was successfully used to treat severe right-sided circulatory failure in both a transplant and a left ventricular assist device recipient.
CONCLUSIONS: If constructed between the femoral vein and artery, such a shunt could (1) be easily inserted and removed, (2) selectively infuse the lower extremities with desaturated blood while maintaining cerebral and cardiac perfusion with saturated blood, (3) selectively reduce the risk of paradoxical emboli to the head and heart, and (4) provide a known and adjustable degree of shunting depending on the condition of the patient, a major advantage of this system compared with creation of an atrial septal defect.

Entities:  

Mesh:

Year:  1995        PMID: 7727466

Source DB:  PubMed          Journal:  J Heart Lung Transplant        ISSN: 1053-2498            Impact factor:   10.247


  1 in total

1.  Acute pressure overload of the right ventricle. Comparison of two models of right-left shunt. Pulmonary artery to left atrium and right atrium to left atrium: experimental study.

Authors:  Mihalis Argiriou; Dimitrios Mikroulis; Timothy Sakellaridis; Vasilios Didilis; Apostolos Papalois; George Bougioukas
Journal:  J Cardiothorac Surg       Date:  2011-10-19       Impact factor: 1.637

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.