| Literature DB >> 7726900 |
C Rougeulle1, L Colleaux, B Dujon, P Avner.
Abstract
The Xist sequence has several characteristics that make it a potential candidate for the X-inactivation center. To investigate the role of Xist and adjacent sequences lying within the X-inactivation center candidate region, a 460-kb region surrounding the murine Xist sequence has been arrayed in lambda contigs with a combination of IRS-PCR-based hybridization and YAC fragmentation. The orientation of the Xist sequence in relation to the telomere and centromere of the X Chromosome (Chr) has been established with this contig and shown to be inverted compared to that in human.Entities:
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Year: 1994 PMID: 7726900 DOI: 10.1007/bf00357001
Source DB: PubMed Journal: Mamm Genome ISSN: 0938-8990 Impact factor: 2.957