Literature DB >> 7726532

Fluconazole penetration into the human prostate.

R W Finley1, J D Cleary, J Goolsby, S W Chapman.   

Abstract

Fluconazole concentrations in the serum and prostate of human volunteers undergoing transurethral resection for benign prostatic hypertrophy were measured. There was a high correlation (r = 0.783) between serum (mean = 6.6 micrograms/ml) and tissue (mean = 1.9 micrograms/g) fluconazole concentrations, and these data were used to construct a model for local tissue concentrations.

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Year:  1995        PMID： 7726532      PMCID： PMC162579          DOI： 10.1128/AAC.39.2.553

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Prostatic cryptococcal infection.

Authors:  C King; R Finley; S W Chapman
Journal:  Ann Intern Med       Date:  1990-11-01       Impact factor: 25.391

Review 2.  Antibiotic tissue penetration and its relevance: models of tissue penetration and their meaning.

Authors:  D E Nix; S D Goodwin; C A Peloquin; D L Rotella; J J Schentag
Journal:  Antimicrob Agents Chemother       Date:  1991-10       Impact factor: 5.191

3.  Persistence of Cryptococcus neoformans in the prostate: failure of fluconazole despite high doses.

Authors:  M P Bailly; A Boibieux; F Biron; I Durieu; M A Piens; D Peyramond; J L Bertrand
Journal:  J Infect Dis       Date:  1991-08       Impact factor: 5.226

4.  Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-1994. A 55-year-old heart-transplant recipient with a tender, enlarged prostate gland.

Authors: 
Journal:  N Engl J Med       Date:  1994-02-17       Impact factor: 91.245

5.  Assay of fluconazole by megabore capillary gas-liquid chromatography with nitrogen-selective detection.

Authors:  S C Harris; J E Wallace; G Foulds; M G Rinaldi
Journal:  Antimicrob Agents Chemother       Date:  1989-05       Impact factor: 5.191

6.  Involvement of the kidney and prostate in cryptococcosis.

Authors:  W R Salyer; D C Salyer
Journal:  J Urol       Date:  1973-04       Impact factor: 7.450

Review 7.  Antibiotic assays in muscle: are conventional tissue levels misleading as indicator of the antibacterial activity?

Authors:  D M Ryan; O Cars
Journal:  Scand J Infect Dis       Date:  1980

8.  Persistent Cryptococcus neoformans infection of the prostate after successful treatment of meningitis. California Collaborative Treatment Group.

Authors:  R A Larsen; S Bozzette; J A McCutchan; J Chiu; M A Leal; D D Richman
Journal:  Ann Intern Med       Date:  1989-07-15       Impact factor: 25.391

Review 9.  Clinical pharmacokinetics of fluconazole.

Authors:  D Debruyne; J P Ryckelynck
Journal:  Clin Pharmacokinet       Date:  1993-01       Impact factor: 6.447

10.  Cryptococcal prostatic abscess associated with the acquired immunodeficiency syndrome.

Authors:  G J Mamo; M A Rivero; S C Jacobs
Journal:  J Urol       Date:  1992-09       Impact factor: 7.450
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  4 in total

1.  Clinical pharmacokinetics of fluconazole in superficial and systemic mycoses.

Authors:  D Debruyne
Journal:  Clin Pharmacokinet       Date:  1997-07       Impact factor: 6.447

Review 2.  Commonly used antibacterial and antifungal agents for hospitalised paediatric patients: implications for therapy with an emphasis on clinical pharmacokinetics.

Authors:  J Singh; B Burr; D Stringham; A Arrieta
Journal:  Paediatr Drugs       Date:  2001       Impact factor: 3.022

3.  Human subcutaneous tissue distribution of fluconazole: comparison of microdialysis and suction blister techniques.

Authors:  Lucy Sasongko; Kenneth M Williams; Richard O Day; Andrew J McLachlan
Journal:  Br J Clin Pharmacol       Date:  2003-11       Impact factor: 4.335

Review 4.  Tissue penetration of antifungal agents.

Authors:  Timothy Felton; Peter F Troke; William W Hope
Journal:  Clin Microbiol Rev       Date:  2014-01       Impact factor: 26.132
  4 in total

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