Literature DB >> 7721104

A novel pituitary transcription factor is produced by alternative splicing of the human GHF-1/PIT-1 gene.

M Delhase1, V Vila, E L Hooghe-Peters, J L Castrillo.   

Abstract

An alternative splice acceptor site in intron 1 of the human GHF-1/PIT-1 gene was sequenced. The use of this splice site is responsible for a 78-bp in-frame insertion upstream from exon 2 and leads to the hGHF-2/PIT-2 cDNA detected in normal human pituitary.

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Year:  1995        PMID： 7721104     DOI： 10.1016/0378-1119(94)00757-j

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  4 in total

1.  The 26-amino acid beta-motif of the Pit-1beta transcription factor is a dominant and independent repressor domain.

Authors:  Matthew D Jonsen; Dawn L Duval; Arthur Gutierrez-Hartmann
Journal:  Mol Endocrinol       Date:  2009-06-25

2.  Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression.

Authors:  A P Bradford; C Wasylyk; B Wasylyk; A Gutierrez-Hartmann
Journal:  Mol Cell Biol       Date:  1997-03       Impact factor: 4.272

Review 3.  Genetic aspects of central hypothyroidism.

Authors:  R Collu
Journal:  J Endocrinol Invest       Date:  2000-02       Impact factor: 4.256

4.  Nuclear factor 1 regulates the distal silencer of the human PIT1/GHF1 gene.

Authors:  F Rajas; M Delhase; M De La Hoya; P Verdood; J L Castrillo; E L Hooghe-Peters
Journal:  Biochem J       Date:  1998-07-01       Impact factor: 3.857
  4 in total

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