Literature DB >> 7719273

Selective digestive decontamination in multiple trauma patients: cost and efficacy.

A Langlois-Karaga1, M Bues-Charbit, A Davignon, J Albanese, O Durbec, C Martin, N Morati, G Balansard.   

Abstract

A double-blind randomized placebo-controlled study was carried out to evaluate the efficacy and the cost of selective digestive decontamination (SDD) to prevent nosocomial pneumonia in multiple-trauma patients. Nosocomial infections, particularly pneumonia, were more frequent in the placebo group. The most common infectious agent was Staphylococcus: Staphylococcus aureus in the placebo group and Staphylococcus epidermidis in the SDD group. Methicillin-resistant Staphylococcus epidermidis was detected more often in the SDD group. No methicillin-resistant Staphylococcus aureus was observed in this study. Fewer patients in the SDD group required antibiotherapy. SDD resulted in a saving of about 41% in drug expenditure.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7719273     DOI： 10.1007/bf01875552

Source DB:  PubMed          Journal:  Pharm World Sci        ISSN： 0928-1231


  30 in total

1.  Double-blind study of selective decontamination of the digestive tract in intensive care.

Authors:  J M Hammond; P D Potgieter; G L Saunders; A A Forder
Journal:  Lancet       Date:  1992-07-04       Impact factor: 79.321

Review 2.  Prevention of pneumonia by selective decontamination of the digestive tract (SDD).

Authors:  C P Stoutenbeek; H K van Saene
Journal:  Intensive Care Med       Date:  1992       Impact factor: 17.440

3.  Short-term parenteral antibiotics used as a supplement to SDD regimens.

Authors:  S R Alcock
Journal:  Infection       Date:  1990       Impact factor: 3.553

4.  Aspiration of gastric bacteria in antacid-treated patients: a frequent cause of postoperative colonisation of the airway.

Authors:  G C du Moulin; D G Paterson; J Hedley-Whyte; A Lisbon
Journal:  Lancet       Date:  1982-01-30       Impact factor: 79.321

5.  Stomach as source of bacteria colonising respiratory tract during artificial ventilation.

Authors:  S T Atherton; D J White
Journal:  Lancet       Date:  1978-11-04       Impact factor: 79.321

6.  Prevention of infection in critically ill patients by selective decontamination of the digestive tract.

Authors:  F R Cockerill; S R Muller; J P Anhalt; H M Marsh; M B Farnell; P Mucha; D J Gillespie; D M Ilstrup; J J Larson-Keller; R L Thompson
Journal:  Ann Intern Med       Date:  1992-10-01       Impact factor: 25.391

7.  Preventing lower airway colonization and infection in mechanically ventilated patients.

Authors:  R van Uffelen; J H Rommes; H K van Saene
Journal:  Crit Care Med       Date:  1987-02       Impact factor: 7.598

8.  A controlled trial of selective decontamination of the digestive tract in intensive care and its effect on nosocomial infection.

Authors:  R Winter; H Humphreys; A Pick; A P MacGowan; S M Willatts; D C Speller
Journal:  J Antimicrob Chemother       Date:  1992-07       Impact factor: 5.790

Review 9.  Nosocomial pneumonia in the intubated patient: role of gastric colonization.

Authors:  D E Craven; F D Daschner
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-01       Impact factor: 3.267

10.  Intestinal decontamination for control of nosocomial multiresistant gram-negative bacilli. Study of an outbreak in an intensive care unit.

Authors:  C Brun-Buisson; P Legrand; A Rauss; C Richard; F Montravers; M Besbes; J L Meakins; C J Soussy; F Lemaire
Journal:  Ann Intern Med       Date:  1989-06-01       Impact factor: 25.391
View more
  7 in total

1.  Cost effectiveness of selective decontamination of the digestive tract in liver transplant patients.

Authors:  P J van Enckevort; J H Zwaveling; J T Bottema; J K Maring; I J Klompmaker; M J Slooff; E M TenVergert
Journal:  Pharmacoeconomics       Date:  2001       Impact factor: 4.981

Review 2.  [Diagnosis and therapy of sepsis].

Authors:  K Reinhart; F M Brunkhorst; H-G Bone; H Gerlach; M Gründling; G Kreymann; P Kujath; G Marggraf; K Mayer; A Meier-Hellmann; C Peckelsen; C Putensen; F Stüber; M Quintel; M Ragaller; R Rossaint; N Weiler; T Welte; K Werdan
Journal:  Clin Res Cardiol       Date:  2006-08       Impact factor: 5.460

Review 3.  [Diagnosis and therapy of sepsis. Guidelines of the German Sepsis Society Inc. and the German Interdisciplinary Society for Intensive and Emergency Medicine].

Authors:  K Reinhart; F Brunkhorst; H Bone; H Gerlach; M Gründling; G Kreymann; P Kujath; G Marggraf; K Mayer; A Meier-Hellmann; C Peckelsen; C Putensen; M Quintel; M Ragaller; R Rossaint; F Stüber; N Weiler; T Welte; K Werdan
Journal:  Internist (Berl)       Date:  2006-04       Impact factor: 0.743

Review 4.  Topical antibiotics as a major contextual hazard toward bacteremia within selective digestive decontamination studies: a meta-analysis.

Authors:  James C Hurley
Journal:  BMC Infect Dis       Date:  2014-12-31       Impact factor: 3.090

5.  Unusually High Incidences of Staphylococcus aureus Infection within Studies of Ventilator Associated Pneumonia Prevention Using Topical Antibiotics: Benchmarking the Evidence Base.

Authors:  James C Hurley
Journal:  Microorganisms       Date:  2018-01-04

6.  Selective decontamination of the digestive tract and selective oropharyngeal decontamination in intensive care unit patients: a cost-effectiveness analysis.

Authors:  Evelien A N Oostdijk; G A de Wit; Marina Bakker; Anne Marie G A de Smet; M J M Bonten
Journal:  BMJ Open       Date:  2013-03-05       Impact factor: 2.692

Review 7.  Single-drug therapy or selective decontamination of the digestive tract as antifungal prophylaxis in critically ill patients: a systematic review.

Authors:  Jw Olivier van Till; Oddeke van Ruler; Bas Lamme; Roy J P Weber; Johannes B Reitsma; Marja A Boermeester
Journal:  Crit Care       Date:  2007       Impact factor: 9.097
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.