OBJECTIVES: To estimate the extent to which the changes in the main cardiovascular risk factors (blood pressure, smoking, and serum cholesterol concentration) can explain the observed changes in mortality from stroke in Finland during the past 20 years. DESIGN: Predicted changes in mortality from cerebrovascular disease mortality were calculated by a proportional hazards model from data obtained in cross sectional population surveys in 1972, 1977, 1982, 1987, and 1992. Predicted changes were compared with the observed changes in mortality statistics. SETTING: North Karelia and Kuopio provinces, Finland. SUBJECTS: 16,741 men and 16,389 women aged 30-59 randomly selected from the national population register, of whom 14,054 men and 14,546 women participated. MAIN OUTCOME MEASURES: Levels of risk factors and predicted and observed changes in mortality from cerebrovascular disease. RESULTS: The observed changes in diastolic blood pressure, total serum cholesterol concentration, and smoking in the population from 1972 to 1992 predicted a 44% fall in mortality from stroke in men and changes in diastolic blood pressure and smoking predicted a 34% fall in women. The observed fall in mortality from stroke was 66% in men and 60% in women. CONCLUSIONS: Two thirds of the fall in mortality from stroke in men and half in women can be explained by changes in the three main cardiovascular risk factors.
OBJECTIVES: To estimate the extent to which the changes in the main cardiovascular risk factors (blood pressure, smoking, and serum cholesterol concentration) can explain the observed changes in mortality from stroke in Finland during the past 20 years. DESIGN: Predicted changes in mortality from cerebrovascular disease mortality were calculated by a proportional hazards model from data obtained in cross sectional population surveys in 1972, 1977, 1982, 1987, and 1992. Predicted changes were compared with the observed changes in mortality statistics. SETTING: North Karelia and Kuopio provinces, Finland. SUBJECTS: 16,741 men and 16,389 women aged 30-59 randomly selected from the national population register, of whom 14,054 men and 14,546 women participated. MAIN OUTCOME MEASURES: Levels of risk factors and predicted and observed changes in mortality from cerebrovascular disease. RESULTS: The observed changes in diastolic blood pressure, total serum cholesterol concentration, and smoking in the population from 1972 to 1992 predicted a 44% fall in mortality from stroke in men and changes in diastolic blood pressure and smoking predicted a 34% fall in women. The observed fall in mortality from stroke was 66% in men and 60% in women. CONCLUSIONS: Two thirds of the fall in mortality from stroke in men and half in women can be explained by changes in the three main cardiovascular risk factors.
Authors: H Ueshima; M Iida; T Shimamoto; M Konishi; K Tsujioka; M Tanigaki; N Nakanishi; H Ozawa; S Kojima; Y Komachi Journal: Prev Med Date: 1980-11 Impact factor: 4.018
Authors: H Tanaka; Y Ueda; M Hayashi; C Date; T Baba; H Yamashita; H Shoji; Y Tanaka; K Owada; R Detels Journal: Stroke Date: 1982 Jan-Feb Impact factor: 7.914
Authors: P Puska; J M Iacono; A Nissinen; E Vartiainen; R Dougherty; P Pietinen; U Leino; U Uusitalo; T Kuusi; E Kostiainen Journal: Prev Med Date: 1985-09 Impact factor: 4.018
Authors: Timo Saaristo; Leena Moilanen; Eeva Korpi-Hyövälti; Mauno Vanhala; Juha Saltevo; Leo Niskanen; Jari Jokelainen; Markku Peltonen; Heikki Oksa; Jaakko Tuomilehto; Matti Uusitupa; Sirkka Keinänen-Kiukaanniemi Journal: Diabetes Care Date: 2010-07-27 Impact factor: 19.112