Literature DB >> 7719025

Mapping of human and murine genes for latent TGF-beta binding protein-2 (LTBP2).

X Li1, W Yin, L Pérez-Jurado, J Bonadio, U Francke.   

Abstract

A novel gene, isolated because of structural similarities to fibrillin, was called LTBP2 when its 4.6-kb transcript was found to encode a protein sequence related to the latent TGF-beta binding protein (LTBP1), which is encoded on human chromosome (Chr) 2, region p12-q22. We have assigned the human and murine LTBP2 loci to regions of conserved synteny on human Chr 11 and mouse Chr 19. By PCR analysis of somatic cell hybrid DNA and fluorescence in situ hybridization, LTBP2 was mapped to human Chr band 11q12 and Ltbp2 to mouse Chr band 19B. Differences between inbred strains were discovered by single-strand conformation analysis of PCR products from the 3' untranslated region. Analysis of BXD and AKXL recombinant inbred strains have placed Ltbp2 between D19Rp19 and Ly10 on proximal mouse Chr 19.

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Year:  1995        PMID： 7719025     DOI： 10.1007/bf00350892

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  21 in total

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Authors:  C L Maslen; G M Corson; B K Maddox; R W Glanville; L Y Sakai
Journal:  Nature       Date:  1991-07-25       Impact factor: 49.962

Review 2.  Transforming growth factors and the regulation of cell proliferation.

Authors:  R M Lyons; H L Moses
Journal:  Eur J Biochem       Date:  1990-02-14

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Authors:  M N Nesbitt; U Francke
Journal:  Chromosoma       Date:  1973       Impact factor: 4.316

4.  Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome.

Authors:  L Pereira; M D'Alessio; F Ramirez; J R Lynch; B Sykes; T Pangilinan; J Bonadio
Journal:  Hum Mol Genet       Date:  1993-07       Impact factor: 6.150

5.  Detecting high-resolution polymorphisms in human coding loci by combining PCR and single-strand conformation polymorphism (SSCP) analysis.

Authors:  S E Poduslo; M Dean; U Kolch; S J O'Brien
Journal:  Am J Hum Genet       Date:  1991-07       Impact factor: 11.025

6.  TGF-beta 1 binding protein: a component of the large latent complex of TGF-beta 1 with multiple repeat sequences.

Authors:  T Kanzaki; A Olofsson; A Morén; C Wernstedt; U Hellman; K Miyazono; L Claesson-Welsh; C H Heldin
Journal:  Cell       Date:  1990-06-15       Impact factor: 41.582

7.  Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

Authors:  X Li; L Pereira; H Zhang; C Sanguineti; F Ramirez; J Bonadio; U Francke
Journal:  Genomics       Date:  1993-12       Impact factor: 5.736

8.  Assignment of the gene for cytoplasmic superoxide dismutase (Sod-1) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse.

Authors:  U Francke; R T Taggart
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

9.  Gene mapping in Mus musculus by interspecific cell hybridization: assignment of the genes for tripeptidase-1 to chromosome 10, dipeptidase-2 to chromosome 18, acid phosphatase-1 to chromosome 12, and adenylate kinase-1 to chromosome 2.

Authors:  U Francke; P A Lalley; W Moss; J Ivy; J D Minna
Journal:  Cytogenet Cell Genet       Date:  1977

10.  Transforming growth factor beta gene maps to human chromosome 19 long arm and to mouse chromosome 7.

Authors:  D Fujii; J E Brissenden; R Derynck; U Francke
Journal:  Somat Cell Mol Genet       Date:  1986-05
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  7 in total

1.  Rapid evolution of human pseudoautosomal genes and their mouse homologs.

Authors:  J W Ellison; X Li; U Francke; L J Shapiro
Journal:  Mamm Genome       Date:  1996-01       Impact factor: 2.957

2.  Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system.

Authors:  Y D Zhou; M Barnard; H Tian; X Li; H Z Ring; U Francke; J Shelton; J Richardson; D W Russell; S L McKnight
Journal:  Proc Natl Acad Sci U S A       Date:  1997-01-21       Impact factor: 11.205

Review 3.  The latent transforming growth factor beta binding protein (LTBP) family.

Authors:  R Oklü; R Hesketh
Journal:  Biochem J       Date:  2000-12-15       Impact factor: 3.857

4.  Parental somatic and germ-line mosaicism for a FBN2 mutation and analysis of FBN2 transcript levels in dermal fibroblasts.

Authors:  E A Putnam; E S Park; C M Aalfs; R C Hennekam; D M Milewicz
Journal:  Am J Hum Genet       Date:  1997-04       Impact factor: 11.025

5.  Solution structure of the transforming growth factor beta-binding protein-like module, a domain associated with matrix fibrils.

Authors:  X Yuan; A K Downing; V Knott; P A Handford
Journal:  EMBO J       Date:  1997-11-17       Impact factor: 11.598

6.  Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1.

Authors:  J Saharinen; J Taipale; J Keski-Oja
Journal:  EMBO J       Date:  1996-01-15       Impact factor: 11.598

7.  Enamel and dental anomalies in latent-transforming growth factor beta-binding protein 3 mutant mice.

Authors:  Supawich Morkmued; Joseph Hemmerle; Eric Mathieu; Virginie Laugel-Haushalter; Branka Dabovic; Daniel B Rifkin; Pascal Dollé; Karen Niederreither; Agnès Bloch-Zupan
Journal:  Eur J Oral Sci       Date:  2017-02       Impact factor: 2.612
  7 in total

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