Literature DB >> 7718743

Novel biopolymers for drug discovery.

E J Moran1, T E Wilson, C Y Cho, S R Cherry, P G Schultz.   

Abstract

The solid phase synthesis and generation of libraries of "unnatural biopolymers" is described. These polymers are characterized by novel backbones and building blocks, the properties of which may modify their pharmacological and folding properties.

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Year:  1995        PMID: 7718743     DOI: 10.1002/bip.360370305

Source DB:  PubMed          Journal:  Biopolymers        ISSN: 0006-3525            Impact factor:   2.505


  2 in total

1.  Solid-phase synthesis of Stat3 inhibitors incorporating O-carbamoylserine and O-carbamoylthreonine as glutamine mimics.

Authors:  Pijus K Mandal; Patricia A Heard; Zhiyong Ren; Xiaomin Chen; John S McMurray
Journal:  Bioorg Med Chem Lett       Date:  2006-11-06       Impact factor: 2.823

2.  Betidamino acids: versatile and constrained scaffolds for drug discovery.

Authors:  J E Rivier; G Jiang; S C Koerber; J Porter; L Simon; A G Craig; C A Hoeger
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-05       Impact factor: 11.205

  2 in total

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