Literature DB >> 7715337

Outcome of transplantation of non-heart-beating donor kidneys.

R M Wijnen1, M H Booster, B M Stubenitsky, J de Boer, E Heineman, G Kootstra.   

Abstract

To reduce the shortage of kidneys for transplantation, we started a non-heart-beating (NHB) donor programme, and compared the short-term and long-term outcomes of kidneys from NHB donors with those of a matched group of kidneys from heart-beating (HB) donors. 57 NHB kidneys were procured at the University Hospital in Maastricht and at three regional hospitals in the Netherlands, and were transplanted in 21 transplant centres within the Eurotransplant exchange organisation. 114 matched controls from HB donors were selected from Eurotransplant files. Mean follow-up was 85 months. At 5 years, graft survival was 54% for NHB kidneys and 55% for HB kidneys; patient survival was 75% and 77%. Kidneys from NHB donors had a significantly higher rate of delayed graft function (60% vs 35%), resulting in a longer hospital stay. Primary non-function of the graft was seen as frequently in the NHB donor-kidney group as in the HB group (14% vs 8%, p = 0.3). We conclude that NHB donors are a valuable source of kidneys for transplantation.

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Year:  1995        PMID: 7715337

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  14 in total

Review 1.  Use of non-heart-beating donors in renal transplantation.

Authors:  R M Kimber; M S Metcalfe; S A White; M L Nicholson
Journal:  Postgrad Med J       Date:  2001-11       Impact factor: 2.401

Review 2.  Assessment of kidney organ quality and prediction of outcome at time of transplantation.

Authors:  Thomas F Mueller; Kim Solez; Valeria Mas
Journal:  Semin Immunopathol       Date:  2011-01-28       Impact factor: 9.623

3.  Liver transplantation from non-heart beating donors.

Authors:  S A White; K R Prasad
Journal:  BMJ       Date:  2006-02-18

Review 4.  Kidney donation after cardiac death.

Authors:  Jacob A Akoh
Journal:  World J Nephrol       Date:  2012-06-06

5.  Ischaemic/reperfusion injury: Role of infliximab.

Authors:  Atul Bagul
Journal:  World J Transplant       Date:  2012-06-24

6.  Early loss of peritubular capillaries after kidney transplantation.

Authors:  Floortje M E G Steegh; Marielle A C J Gelens; Fred H M Nieman; Johannes P van Hooff; Jack P M Cleutjens; Robert Jan van Suylen; Mat J A P Daemen; Ernst L W van Heurn; Maarten H L Christiaans; Carine J Peutz-Kootstra
Journal:  J Am Soc Nephrol       Date:  2011-05-12       Impact factor: 10.121

7.  Kidneys from donors after cardiac death provide survival benefit.

Authors:  Maarten G Snoeijs; Douglas E Schaubel; Ronald Hené; Andries J Hoitsma; Mirza M Idu; Jan N Ijzermans; Rutger J Ploeg; Jan Ringers; Maarten H Christiaans; Wim A Buurman; L W Ernest van Heurn
Journal:  J Am Soc Nephrol       Date:  2010-05-20       Impact factor: 10.121

Review 8.  The role of innate immunity in donor organ procurement.

Authors:  Dianne B McKay
Journal:  Semin Immunopathol       Date:  2011-03-23       Impact factor: 9.623

9.  The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury.

Authors:  Bart de Vries; Sarah J Walter; Carine J Peutz-Kootstra; Tim G A M Wolfs; L W Ernest van Heurn; Wim A Buurman
Journal:  Am J Pathol       Date:  2004-11       Impact factor: 4.307

Review 10.  Current state of hypothermic machine perfusion preservation of organs: The clinical perspective.

Authors:  Michael J Taylor; Simona C Baicu
Journal:  Cryobiology       Date:  2009-10-24       Impact factor: 2.487

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