Literature DB >> 7714744

Potentiometric determination of the partition and distribution coefficients of dianionic compounds.

F H Clarke1, N M Cahoon.   

Abstract

The potentiometric determination of the partition and distribution coefficients of two dianionic hexapeptide derivatives is described. For each of these compounds, the partition coefficient of the dianion makes the largest contribution to the distribution coefficient at pH 7.4.

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Year:  1995        PMID: 7714744     DOI: 10.1002/jps.2600840113

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

1.  Hydrophobicity of HIV protease inhibitors by immobilized artificial membrane chromatography: application and significance to drug transport.

Authors:  B H Stewart; F Y Chung; B Tait; C J Blankley; O H Chan; C John
Journal:  Pharm Res       Date:  1998-09       Impact factor: 4.200

  1 in total

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