Literature DB >> 7714665

Review of in vivo pharmacokinetics and toxicology of phosphorothioate oligonucleotides.

S K Srinivasan1, P Iversen.   

Abstract

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Year:  1995        PMID： 7714665     DOI： 10.1002/jcla.1860090210

Source DB:  PubMed          Journal:  J Clin Lab Anal        ISSN： 0887-8013            Impact factor:   2.352


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  16 in total

1.  Developing aptamers into therapeutics.

Authors:  R R White; B A Sullenger; C P Rusconi
Journal:  J Clin Invest       Date:  2000-10       Impact factor: 14.808

Review 2.  Preclinical and clinical pharmacology of antisense oligonucleotides.

Authors:  E G Marcusson; B R Yacyshyn; W R Shanahan; N M Dean
Journal:  Mol Biotechnol       Date:  1999-08       Impact factor: 2.695

3.  A competitive enzyme hybridization assay for plasma determination of phosphodiester and phosphorothioate antisense oligonucleotides.

Authors:  J R Deverre; V Boutet; D Boquet; E Ezan; J Grassi; J M Grognet
Journal:  Nucleic Acids Res       Date:  1997-09-15       Impact factor: 16.971

4.  Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids.

Authors:  M Gilar; A Belenky; D L Smisek; A Bourque; A S Cohen
Journal:  Nucleic Acids Res       Date:  1997-09-15       Impact factor: 16.971

Review 5.  Managing the sequence-specificity of antisense oligonucleotides in drug discovery.

Authors:  Peter H Hagedorn; Bo R Hansen; Troels Koch; Morten Lindow
Journal:  Nucleic Acids Res       Date:  2017-03-17       Impact factor: 16.971

6.  A cytosine analog that confers enhanced potency to antisense oligonucleotides.

Authors:  W M Flanagan; J J Wolf; P Olson; D Grant; K Y Lin; R W Wagner; M D Matteucci
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-30       Impact factor: 11.205

7.  Characterization of Apolipoprotein C3 (Apo C3) LNA/DNA Impurities and Degradation Products by LC-MS/MS.

Authors:  Olga V Friese; Justin B Sperry; Yan He; Liji Joseph; James A Carroll; Jason C Rouse
Journal:  AAPS J       Date:  2017-05-09       Impact factor: 4.009

8.  Sulfur-centered hemi-bond radicals as active intermediates in S-DNA phosphorothioate oxidation.

Authors:  Jialong Jie; Ye Xia; Chun-Hua Huang; Hongmei Zhao; Chunfan Yang; Kunhui Liu; Di Song; Ben-Zhan Zhu; Hongmei Su
Journal:  Nucleic Acids Res       Date:  2019-12-16       Impact factor: 16.971

9.  In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells.

Authors:  M K Bijsterbosch; M Manoharan; E T Rump; R L De Vrueh; R van Veghel; K L Tivel; E A Biessen; C F Bennett; P D Cook; T J van Berkel
Journal:  Nucleic Acids Res       Date:  1997-08-15       Impact factor: 16.971

10.  Fatty Acid-Modified Gapmer Antisense Oligonucleotide and Serum Albumin Constructs for Pharmacokinetic Modulation.

Authors:  Michael Lykke Hvam; Yunpeng Cai; Frederik Dagnæs-Hansen; Jesper Sejrup Nielsen; Jesper Wengel; Jørgen Kjems; Kenneth A Howard
Journal:  Mol Ther       Date:  2017-06-20       Impact factor: 11.454
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