Literature DB >> 7712121

Peptidomimetic antagonists designed to inhibit the binding of CD4 to HIV GP120.

S Ramurthy1, M S Lee, H Nakanishi, R Shen, M Kahn.   

Abstract

Attempts to enhance the efficacy of our previously reported CD4 CDR2-like (residues 40-45) mimetic 1 by incorporation of the critical guanidine residue Arg-59 of CD4 are described.

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Year:  1994        PMID: 7712121     DOI: 10.1016/s0968-0896(00)82049-0

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  1 in total

1.  Research on anti-HIV-1 agents. Investigation on the CD4-Suradista binding mode through docking experiments.

Authors:  F Manetti; F Corelli; N Mongelli; A L Borgia; M Botta
Journal:  J Comput Aided Mol Des       Date:  2000-05       Impact factor: 3.686

  1 in total

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