Literature DB >> 7711406

Urinary zinc excretion and acute phase response in cancer patients.

B Melichar1, P Jandik, M Tichy, F Malir, J Mergancova, Z Voboril.   

Abstract

We investigated urinary zinc and serum levels of C-reactive protein, alpha-1 acid glycoprotein, haptoglobin, transferrin and prealbumin in 55 patients with solid tumors and 20 controls. Urinary zinc, serum C-reactive protein, alpha-1 acid glycoprotein and haptoglobin were significantly higher, and serum prealbumin was significantly lower in cancer patients. A significant positive correlation between urinary zinc and C-reactive protein, alpha-1 acid glycoprotein and haptoglobin, as well as a negative correlation with transferrin and prealbumin were observed. Hyperzincuria in cancer patients appears to be linked to the acute phase response. Our data provide further evidence implicating systemic inflammatory response in increased urinary zinc excretion.

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Year:  1994        PMID： 7711406     DOI： 10.1007/bf00577746

Source DB:  PubMed          Journal:  Clin Investig        ISSN： 0941-0198


  18 in total

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Journal:  Clin Sci (Lond)       Date:  1993-03       Impact factor: 6.124

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Journal:  Am J Surg       Date:  1982-09       Impact factor: 2.565

5.  Urinary excretion of zinc and iron following injection of bacteria in the unanesthetized rabbit.

Authors:  K A Kirby; B A Rothenburg; W Victery; A J Vander; M J Kluger
Journal:  Miner Electrolyte Metab       Date:  1982

6.  Effect of renal transplantation on zinc metabolism and taste acuity in uremia. A prospective study.

Authors:  S K Mahajan; J Abraham; S D Migdal; D K Abu-Hamdan; F D McDonald
Journal:  Transplantation       Date:  1984-12       Impact factor: 4.939

7.  Role of iron in postischemic renal injury in the rat.

Authors:  M S Paller; B E Hedlund
Journal:  Kidney Int       Date:  1988-10       Impact factor: 10.612

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Journal:  Am J Med       Date:  1985-08       Impact factor: 4.965

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Journal:  J Lab Clin Med       Date:  1991-12

10.  Acute-phase proteins or tumour markers: the role of SAA, SAP, CRP and CEA as indicators of metastasis in a broad spectrum of neoplastic diseases.

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Journal:  Scand J Immunol       Date:  1984-03       Impact factor: 3.487
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  2 in total

1.  Zinc status of patients with benign prostatic hyperplasia and prostate carcinoma.

Authors:  Pamela Christudoss; R Selvakumar; Joseph J Fleming; Ganesh Gopalakrishnan
Journal:  Indian J Urol       Date:  2011-01

2.  The potential of spot urine as a biomarker for zinc assessment in Malawian children and adults.

Authors:  Blessings H Likoswe; R Murray Lark; John Phuka; Kenneth Maleta; Edward Joy; Nicola M Lowe
Journal:  Front Nutr       Date:  2022-07-22
  2 in total

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