Literature DB >> 7711080

Cloning and sequence analysis of human thyroid transcription factor 1.

A Saiardi1, V Tassi, V De Filippis, D Civitareale.   

Abstract

The thyroid transcription factor 1 (TTF-1) is a homeodomain-containing transcription factor that activates the transcriptional activity of thyroid-specific gene promoters by binding to them. Hence, TTF-1 is crucial in the maintenance of the thyroid differentiation phenotype. The authors isolated and analysed the human TTF-1 gene, which shows a striking homology with the rat TTF-1 gene.

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Year:  1995        PMID: 7711080     DOI: 10.1016/0167-4781(95)00034-e

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  1 in total

1.  Combined ultrasound and isotope scanning is more informative in the diagnosis of congenital hypothyroidism than single scanning.

Authors:  R J Perry; S Maroo; A C Maclennan; J H Jones; M D C Donaldson
Journal:  Arch Dis Child       Date:  2006-07-24       Impact factor: 3.791

  1 in total

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