Literature DB >> 7710717

Autoantibodies in scleroderma and tightskin mice.

C Bona1, N Rothfield.   

Abstract

There is much evidence to suggest that scleroderma in human patients is caused by a fundamental defect in the immune system. In tightskin mice, the scleroderma syndrome is associated with autoimmunity, particularly autoantibodies interacting with scleroderma target antigens.

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Year:  1994        PMID： 7710717     DOI： 10.1016/0952-7915(94)90016-7

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  15 in total

Review 1.  T cells and B cells in the pathogenesis of systemic sclerosis: recent insights and therapeutic opportunities.

Authors:  Francesco Del Galdo; Carol M Artlett
Journal:  Curr Rheumatol Rep       Date:  2006-04       Impact factor: 4.592

2.  B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis.

Authors:  Minoru Hasegawa; Yasuhito Hamaguchi; Koichi Yanaba; Jean-David Bouaziz; Junji Uchida; Manabu Fujimoto; Takashi Matsushita; Yukiyo Matsushita; Mayuka Horikawa; Kazuhiro Komura; Kazuhiko Takehara; Shinichi Sato; Thomas F Tedder
Journal:  Am J Pathol       Date:  2006-09       Impact factor: 4.307

3.  CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.

Authors:  Eriko Saito; Manabu Fujimoto; Minoru Hasegawa; Kazuhiro Komura; Yasuhito Hamaguchi; Yuko Kaburagi; Tetsuya Nagaoka; Kazuhiko Takehara; Thomas F Tedder; Shinichi Sato
Journal:  J Clin Invest       Date:  2002-06       Impact factor: 14.808

Review 4.  Molecular aspects of regulation of collagen gene expression in fibrosis.

Authors:  Rashpal K Bhogal; Cristina M Stoica; Tracy L McGaha; Constantin A Bona
Journal:  J Clin Immunol       Date:  2005-11       Impact factor: 8.317

5.  Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts.

Authors:  Takao Kodera; Tracy L McGaha; Robert Phelps; William E Paul; Constantin A Bona
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-12       Impact factor: 11.205

6.  Clinical significance of serum HMGB-1 and sRAGE levels in systemic sclerosis: association with disease severity.

Authors:  Ayumi Yoshizaki; Kazuhiro Komura; Yohei Iwata; Fumihide Ogawa; Toshihide Hara; Eiji Muroi; Motoi Takenaka; Kazuhiro Shimizu; Minoru Hasegawa; Manabu Fujimoto; Shinichi Sato
Journal:  J Clin Immunol       Date:  2008-09-30       Impact factor: 8.317

7.  B Lymphocyte signaling established by the CD19/CD22 loop regulates autoimmunity in the tight-skin mouse.

Authors:  Noriko Asano; Manabu Fujimoto; Norihito Yazawa; Senji Shirasawa; Minoru Hasegawa; Hitoshi Okochi; Kunihiko Tamaki; Thomas F Tedder; Shinichi Sato
Journal:  Am J Pathol       Date:  2004-08       Impact factor: 4.307

8.  Over-expression of TATA binding protein (TBP) and p53 and autoantibodies to these antigens are features of systemic sclerosis, systemic lupus erythematosus and overlap syndromes.

Authors:  R Chauhan; R Handa; T P Das; U Pati
Journal:  Clin Exp Immunol       Date:  2004-06       Impact factor: 4.330

9.  Polymorphism of immunoglobulin enhancer element HS1,2A: allele *2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequency.

Authors:  D Frezza; V Giambra; B Tolusso; M De Santis; S Bosello; S Vettori; G Triolo; G Valentini; G Ferraccioli
Journal:  Ann Rheum Dis       Date:  2007-03-28       Impact factor: 19.103

10.  The role of B cells in systemic sclerosis.

Authors:  Marina D Kraaij; Jacob M van Laar
Journal:  Biologics       Date:  2008-09
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