M Touger1, E J Gallagher, J Tyrell. 1. Department of Medicine, Bronx Municipal Hospital, Albert Einstein College of Medicine.
Abstract
STUDY OBJECTIVE: To test the hypothesis that venous carboxyhemoglobin (V-COHb) levels accurately predict arterial (A-COHb) levels. DESIGN: Prospective comparison of A-COHb and V-COHb levels in patients with suspected carbon monoxide (CO) poisoning. SETTING: Municipal hospital emergency department with contiguous multiplace hyperbaric chamber staffed 24 hours a day. PARTICIPANTS: Unselected convenience sample of 61 adults with suspected CO toxicity. INTERVENTION: Simultaneous sampling of arterial and venous blood. RESULTS: Correlation between V-COHb and A-COHb showed an r value of .99 (95%CI, .99 to .99), and an r2 value of .98. Agreement between V-COHb and A-COHb levels was examined by use of a plot of arteriovenous differences against the mean of the two measurements. The mean arteriovenous difference was .15% COHb (95%CI, .13% to .45%), with 95% of the differences ranging from 2.4% COHb to -2.1% COHb. CONCLUSION: Venous COHb levels predict arterial levels with a high degree of accuracy. Patients with suspected CO poisoning can be screened with the use of venous blood, without the need for arterial puncture.
STUDY OBJECTIVE: To test the hypothesis that venous carboxyhemoglobin (V-COHb) levels accurately predict arterial (A-COHb) levels. DESIGN: Prospective comparison of A-COHb and V-COHb levels in patients with suspected carbon monoxide (CO) poisoning. SETTING: Municipal hospital emergency department with contiguous multiplace hyperbaric chamber staffed 24 hours a day. PARTICIPANTS: Unselected convenience sample of 61 adults with suspected COtoxicity. INTERVENTION: Simultaneous sampling of arterial and venous blood. RESULTS: Correlation between V-COHb and A-COHb showed an r value of .99 (95%CI, .99 to .99), and an r2 value of .98. Agreement between V-COHb and A-COHb levels was examined by use of a plot of arteriovenous differences against the mean of the two measurements. The mean arteriovenous difference was .15% COHb (95%CI, .13% to .45%), with 95% of the differences ranging from 2.4% COHb to -2.1% COHb. CONCLUSION: Venous COHb levels predict arterial levels with a high degree of accuracy. Patients with suspected COpoisoning can be screened with the use of venous blood, without the need for arterial puncture.
Authors: Derek M Culnan; Beretta Craft-Coffman; Genevieve H Bitz; Karel D Capek; Yiji Tu; William C Lineaweaver; Maggie J Kuhlmann-Capek Journal: Ann Plast Surg Date: 2018-03 Impact factor: 1.539
Authors: Laura E Fredenburgh; Bryan D Kraft; Dean R Hess; R Scott Harris; Monroe A Wolf; Hagir B Suliman; Victor L Roggli; John D Davies; Tilo Winkler; Alex Stenzler; Rebecca M Baron; B Taylor Thompson; Augustine M Choi; Karen E Welty-Wolf; Claude A Piantadosi Journal: Am J Physiol Lung Cell Mol Physiol Date: 2015-08-28 Impact factor: 5.464