Literature DB >> 7709385

[Problems when swallowing tablets. A questionnaire study from general practice].

O Andersen1, O K Zweidorff, T Hjelde, E A Rødland.   

Abstract

Dysphagia, or difficulty in swallowing tablets, may greatly affect compliance. This report presents the results of our survey, which was undertaken to determine the proportion of a general practitioner's patient population who had difficulty in swallowing tablets, and to identify the reasons for the difficulty. 6,158 questionnaires were received from patients who consulted a general practitioner. More than 1/4 (26%) of the total patient population (or 1,576) said they had problems in swallowing tablets. A prominent complaint was the size of the tablet, followed by the surface, form and taste of the tablet. Twice as many women as men experienced swallowing problems. Elderly patients (> 70 years) had less difficulty than younger patients when taking tablets. To achieve good compliance and optimal pharmacotherapy, it is important for medical practitioners and pharmaceutical personnel to be aware of the general problems connected to swallowing tablets, to enable them to select the correctly formulated drug for their patients. New and novel oral drug formulations, such as tablets that dissolve in seconds on the tongue without water, may alleviate the problem of swallowing tablets. They offer substantial advantages over ordinary tablets, are more convenient to administer, and enhance the potential for improved compliance in patients who experience difficulty in taking tablets.

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Year:  1995        PMID: 7709385

Source DB:  PubMed          Journal:  Tidsskr Nor Laegeforen        ISSN: 0029-2001


  21 in total

1.  Development and evaluation of an oral fast disintegrating anti-allergic film using hot-melt extrusion technology.

Authors:  Manjeet B Pimparade; Anh Vo; Abhijeet S Maurya; Jungeun Bae; Joseph T Morott; Xin Feng; Dong Wuk Kim; Vijay I Kulkarni; Roshan Tiwari; K Vanaja; Reena Murthy; H N Shivakumar; D Neupane; S R Mishra; S N Murthy; Michael A Repka
Journal:  Eur J Pharm Biopharm       Date:  2017-06-06       Impact factor: 5.571

2.  A randomized cross-over study to evaluate the swallow-enhancing and taste-masking properties of a novel coating for oral tablets.

Authors:  Virgilijus Uloza; Ingrida Uloziene; Egle Gradauskiene
Journal:  Pharm World Sci       Date:  2010-06-04

3.  Difficulties swallowing solid oral dosage forms in a general practice population: prevalence, causes, and relationship to dosage forms.

Authors:  Julia T Schiele; Renate Quinzler; Hans-Dieter Klimm; Markus G Pruszydlo; Walter E Haefeli
Journal:  Eur J Clin Pharmacol       Date:  2012-09-29       Impact factor: 2.953

4.  Establishing compliance with liquid medication administration in a child with autism.

Authors:  Averil Schiff; Jonathan Tarbox; Taira Lanagan; Peter Farag
Journal:  J Appl Behav Anal       Date:  2011

5.  Patients' evaluation of shape, size and colour of solid dosage forms.

Authors:  A B Overgaard; J Højsted; R Hansen; J Møller-Sonnergaard; L L Christrup
Journal:  Pharm World Sci       Date:  2001-10

6.  A randomized, crossover design study of sevelamer carbonate powder and sevelamer hydrochloride tablets in chronic kidney disease patients on haemodialysis.

Authors:  Stanley Fan; Calum Ross; Sandip Mitra; Philip Kalra; Jeremy Heaton; John Hunter; Melissa Plone; Nick Pritchard
Journal:  Nephrol Dial Transplant       Date:  2009-08-07       Impact factor: 5.992

7.  Attitude and perception of patients and health care practitioners toward oral sustained release dosage forms in Palestine.

Authors:  Abdel Naser Zaid
Journal:  Saudi Pharm J       Date:  2010-07-30       Impact factor: 4.330

8.  Swallowing difficulties with oral drugs among polypharmacy patients attending community pharmacies.

Authors:  Julien Marquis; Marie-Paule Schneider; Valérie Payot; Anne-Christine Cordonier; Olivier Bugnon; Kurt E Hersberger; Isabelle Arnet
Journal:  Int J Clin Pharm       Date:  2013-08-21

9.  A qualitative study of the problems surrounding medicine administration to patients with dysphagia.

Authors:  Jennifer Kelly; Gibson D'Cruz; David Wright
Journal:  Dysphagia       Date:  2008-08-08       Impact factor: 3.438

10.  Adolescents' struggles with swallowing tablets: barriers, strategies and learning.

Authors:  Dana Lee Hansen; Ditte Tulinius; Ebba Holme Hansen
Journal:  Pharm World Sci       Date:  2007-06-27
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